We, at Eagle Biosciences, Inc. are rapidly expanding our selection of Coronavirus Assays by welcoming two new research kits! With the ongoing pandemic, it’s more important now than ever that we continue to offer the highest quality assays to our customers. Here are our newest additions;


Anti-SARS-CoV-2 S1 (RBD) IgG ELISA Assay
Catalog Number: E111

The Anti-SARS-CoV-2 S1 (RBD) IgG ELISA Assay Kit is manufactured in Germany by Mediagnost. This assay is a highly specific enzyme immunoassay for the detection of IgG antibodies directed against SARS-CoV-2-S1 Receptor Binding Domain (RBD) in human blood. In this assay the recombinant Receptor Binding Domain (RBD) of SARS-CoV-2 S1 spike protein, which binds the ACE2 receptor, is used. The use of RBD increases the specificity of the assay since the domain is identical with SARS-CoV but not with MERS-CoV for example. Antibodies directed against the RBD neutralize both virus strains SARS-CoV and SARS-CoV-2.

Size: 1×96 wells
Incubation Time: 2 hours 40 minutes
Sample Type: Serum and Plasma
Sample Size: 100 µl
Controls Included

To learn more about the Anti-SARS-CoV-2 S1 (RBD) IgG ELISA Assay click here*


Anti-SARS-CoV-2 (S1, S2, N) IgG ELISA Assay Kit
Catalog Number: 3940

The Anti-SARS-CoV-2 (S1, S2, N) IgG ELISA Assay Kit is manufactured in Germany by Generic Assays. This assay is a module based Enzyme Immunoassay for the confirmation of positive IgG antibodies against SARS coronavirus 2 (SARS-CoV-2) in the first screening. The Anti-SARS-CoV-2 (S1, S2, N) IgG ELISA Assay Kit determines the specificity of antibodies against the main immunodominant antigens (Spike Glycoprotein 1, Spike Glycoprotein 2, Nucleocapsid) of SARS-CoV-2 in human serum or plasma. This test kit consists of modules separately coated with the major antigens of the virus as seen in the illistration below:

Size: 96 wells (24 samples x 4)
Incubation Time: 2 hours
Sample Type: Serum or Plasma
Number Of Tests Per Kit: 24 (22 samples + controls)
Sample Size: 50 µl
Controls Included

To learn more about the Anti-SARS-CoV-2 (S1, S2, N) IgG ELISA Assay Kit click here*

 

Check out our entire Coronavirus Series here or contact us with any questions or inquires

 

*These kits are for research use only and should not be used for diagnostic procedures.

Eagle Biosciences, Inc. is excited to announce the launch of two new assays to help with the growing epidemic of the COVID-19 virus that is spreading worldwide. The COVID-19 IgG and IgM ELISA’s are successfully validated assays for the qualitative detection of novel coronavirus infected pneumonia cases, suspected clustering cases, and other new coronaviruses in serum or plasma samples (COVID-19) through measurement of the COVID-19 IgM or IgG antibodies.

Assay Background
2019 novel coronavirus (COVID-19) is a single-stranded RNA coronavirus. Comparisons of the genetic sequences of is virus have shown similarities to SARS-CoV and bat coronaviruses. In humans, coronaviruses cause respiratory infections. Coronaviruses are composed of several proteins including the spike (S), envelope (E), membrane (M), and nucleocapsid (N). Results suggest that the spike protein retains sufficient affinity to the Angiotensin converting enzyme 2 (ACE2) receptor to use it as a mechanism of cell entry. Human to human transmission of coronaviruses is primarily thought to occur among close contacts via respiratory droplets generated by sneezing and coughing. IgM is the first immunoglobulin to be produced in response to an antigen and will be primarily detectable during the early onset of the disease.

Assay Principle
These COVID-19 IgG and IgM ELISA assay kits are designed, developed, and produced for the qualitative measurement of the COVID-19 IgM or COVID-19 IgG antibody in serum. The assays utilizes the “IgM capture” or “IgG capture” methods on microplate based enzyme immunoassay technique.

Assay controls and samples are added to the microtiter wells of a microplate that was coated with an anti-human IgM or IgG specific antibodies. After the first incubation period, the unbound protein matrix is removed with a subsequent washing step. A horseradish peroxidase (HRP) labeled recombinant COVID-19 antigen is added to each well. After an incubation period, an immunocomplex of Anti-hIgM or Anti-hIgG antibody – human COVID-19 IgM or IgG antibody – HRP labeled COVID-19 antigen is formed if there is novel coronavirus IgM or IgG antibody present in the tested materials. The unbound tracer antigen is removed by the subsequent washing step. HRP-labeled COVID-19 antigen tracer bound to the well is then incubated with a substrate solution in a timed reaction and then measured in a spectrophotometric microplate reader. The enzymatic activity of the tracer antigen bound to the coronavirus IgM of IgG on the wall of the microtiter well is proportional to the amount of the coronavirus IgM or IgG antibody level in the tested materials

To learn more, view assay’s here or contact us for questions! 
Novel Coronavirus COVID-19 IgM ELISA Kit
Novel Coronavirus COVID-19 IgG ELISA Kit

2018 was a big year here at Eagle Biosciences, and 2019 is expected to be even better! We will be making appearances at many tradeshows and conferences this year!

Endo2019
March 23rd-26th
New Orleans, LA
Booth #1930

AACR Annual Meeting
March 29th-April 3rd
Atlanta, GA
Booth #4644

AACC Annual Meeting
August 4th-8th
Anaheim, CA
*Attending, but will not have a booth. Email us if you would like to set up a meeting time

The Association of Medical Laboratory Immunologists (AMLI) Annual Scientific Meeting
August 16th-19th
Cleveland, OH
Booth #8

American Society for Bone and Mineral Research (ASBMR) Annual Meeting
September 20th-23rd
Orlando, FL
Booth #626

ASN Kidney Week
November 5th-10th
Washington, DC
Booth #2005

Medica Tradefair 
November 18th-21st
Düsseldorf, Germany

We’d love to meet you!

If you will be attending any of these events, stop by and say hi! Or set up a meeting if you have any big plans you’d like to talk about

 

Eagle Biosciences, Inc. is excited to collaborate with Austrian biotech Fianostics, to offer a new fluorescence-based detection platform for immunoassays, called FluoBolt™, which enables highly sensitive assays with high reproducibility and reliability. This dramatically improves the informative value of research with biomarkers.

So far, Fianostics FluoBolt™ Metal Enhanced Fluorescence Immunoassays have been developed to detect

What Makes These Assays Different?

Fianostics FluoBolt™ Metal Enhanced Fluorescence Immunoassays have been established to eliminate the complicated processes that come with your standard sandwich ELISA. By using their FluoBolt™ Metal Enhanced Fluorescence Immunoassays, you can expect

  • High Sensitivity!
  • Single Step Assay Procedure!
  • No Enzyme Substrate!
  • Stable Signal over Time!
  • 100% Compatibility with 96-well ELISA Format!

About Fianostics

Fianostics combines scientific and technical expertise in diagnostics with the development of a high-tech detection platform that benefits in reproducibility from the excellent expertise of Sony DADC BioSciences in the production of polymer consumables for the diagnostic industry. Their know-how is not limited to the development of the new detection platform, but we also provide the diagnostic application with the appropriate immunoassays for specific clinical areas. (for research use only in the US)

About Metal Enhanced Fluorescence

Metal Enhanced Fluorescence (MEF) offers the possibility to dramatically increase the analytical sensitivity of systems based on fluorescence detection. MEF is based on the fact that excitation light interacts with the electrons of metal nano–structures thus generating very high electromagnetic fields (Localised Surface Plasmons, LSPs ) Therefore, such structures are also called
”plasmonic structures” and the combination of (e.g, polymeric) support and structure is known as “plasmonic substrate”. These LSPs lead to an increase in emission output of fluorescent molecules (e.g. fluorescently labelled antibodies) when bound to surfaces with suitable nano-metal structures that can enhance the signal more than 100 times.

Hello Loyal Customers!

Our team here at Eagle Biosciences, Inc. are so excited to introduce our new look for you to enjoy! The new EagleBio.com comes chocked-full of new features that will make your browsing and shopping experience far superior to what you’re used to!

  • Speak with one of our team members online when you need help
  • Fast, easy and secure check out
  • Smooth navigation while browsing one of our many unique products

But That’s Not All…

Not only have we made your shopping experience better when you choose to order from Eagle Biosciences, but we are also working with some phenomenal new partners to bring you new and unique products! Here’s a sneak peak…

  • Fianostics FluoBolt™-FIAs : Metal enhanced fluorescence assays that offers a higher sensitivity, single-step alternative to your basic ELISA. Available for detection of Noggin, Asporin, and Periostin! As well as services to test a variety of other markers!
  • osteomiR testing by TAmiRNA : Workflow that detects 11 microRNA associated with bone quality. We will feature osteomiR Test Kit, as well as services that can run your samples for you.
  • New and unique Drug Monitoring Assays

As always, we appreciate your business! Without you we wouldn’t be able to do what we love by providing you the products you need to change the future! Be sure to keep an eye out for more to come.


If you want to see anything from Eagle Biosciences (products, services, etc.) Let us know! We’re here for you!