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EagleBio Participates in 3rd Annual Gate City Marathon and Relay

by Eagle Biosciences


                 EagleBio Senior Team 

EagleBio participated in the 3rd annual Gate City Marathon & Relay on Sunday, May 21, 2017.  This is EagleBio’s 3rd year participating with a relay team full of rock stars!! Our group ran in the race as a 5 leg relay on a 26.2-mile course that took runners past historic former mills, rivers, parks and neighborhoods. 

This team once again amazed their fans and trimmed off 27 minutes from last year’s time! What a race day it was with fantastic weather, great course, helpful officials, and supportive crowd!  



                        EagleBio Junior Team: NYOKO

We were also very lucky to have a 2nd relay team again this year, the Junior EagleBio Team: NYOKO! This team was outstanding, they won FIRST PLACE out of all the relay teams and yes they beat the senior team above (by a lot)!

Great job, NYOKO!

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Nebraska Study Utilized EagleBio’s Secretory IgA (sIgA) ELISA

by Eagle Biosciences

Image 1

 

EagleBio’s Secretory
IgA (SIgA) ELISA Assay Kit was recently used in a Nebraska study. This assay is part of our Immunology Assay Kit line which is comprised of a unique,versatile set of products for a variety
of applications, research, and fields of study.
Check the product pages for full details on the kit or view the links
below to find a new publication referencing our Secretory
IgA (SIgA) ELISA Assay Kit.

Morrow, J. et.
al. Assessing the Archaeoparasitological
Potential of Quids As a Source Material for Immunodiagnostic Analyses. Korean
J Parasitol. 2016 Oct; 54(5): 605–616. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5127539/

“An additional
ELISA test targeting secretory IgA (sIgA) was conducted to further examine the
failure to detect parasite-induced antibodies from quids. Herein, the methods
used for quid preparation and ELISA procedures are described so that they can
be further developed by future researchers. The results are discussed in light
of the potential future of quid analysis.” Read More

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New Product Introduction: iLite FGF-21 Assay Ready Cells

by Eagle Biosciences

iLite® FGF-21 Activity Assays

First products available NOW, many more coming soon!

Image result for Euro Diagnostica

iLite® FGF-21 Assay Ready Cells

The iLite® FGF21 Assay Ready Cells can be used in an assay for the quantification of the potency of analogues of human FGF21, the potency of FGFR1c antagonists or a neutralizing antibody response against such products in human serum in the absence of serum matrix effects.

Developed by:

Key benefits of iLite® FGF-21 Assay Ready Cells:

  • Unparalleled sensitivity (>10 fold inductions)
  • Highly specific reporter gene cell lines
  • Normalization read-out included
  • Negative control available for screening of unspecific activity
  • Easy to use – ready-to-use from the freezer, without culturing of cells

LIMITED OFFER!

50% off on your first iLite® FGF-21 Assay Ready Cells
Use Code: ADCC50 

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Study Shows How BPA May Affect Inflammatory Breast Cancer

by Eagle Biosciences

        image credit: https://corporate.dukehealth.org

DURHAM, N.C. — The chemical bisphenol A, or BPA, appears to aid the survival of inflammatory breast cancer cells, revealing a potential mechanism for how the disease grows, according to a study led by researchers in the Department of Surgery at Duke University School of Medicine and the Duke Cancer Institute.

Read More


Source: (https://corporate.dukehealth.org)

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Webinar: Unique, Early Biomarker for Cell Proliferation

by Eagle Biosciences

 

Eagle Biosciences and AroCell are pleased to invite you to a
webinar on the application of the TK
210 (Thymidine Kinase 1) ELISA in the study of malignancies.

There are many biomarkers of tumor mass, but few serum
biomarkers of tumor proliferation, a key indicator when making prognoses
and choosing and monitoring therapy.

The assay of serum Thymidine Kinase 1 with the AroCell TK 210
ELISA has the potential to be such a biomarker. There is no cost for
this event.

 

When: March
23, 2017 | 11 am to 11:30 am EDT

Presenters:

  • Staffan Eriksson, Professor in Medical and Physiological Chemistry, Swedish
    University of Agricultural Sciences
  • Martin
    Shaw    , Business Development Manager at AroCell.

Key points of the presentation will be:

  • Thymidine
    kinase 1 (TK1) is a well-known proliferation biomarker but most
    current methods are based on enzyme activity methods and may
    underestimate serum TK1 levels, particularly in subjects with solid
    tumors
  • The AroCell
    TK 210 ELISA adds value to studies with existing tumor biomarkers
  • Data will be
    presented on the value of the AroCell TK 210 ELISA in the study of a
    range of hematological and solid tumors.

Receive a white paper on the use of TK1 and the AroCell TK210 ELISA in studying solid tumors HERE

 

 

About AroCell

AroCell AB was founded in 2003. The company is located in Uppsala, Sweden and develops and commercializes tests that can be used in the prognosis, monitoring and follow-up of cancer.
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EagleBIo’s Intact FGF-21 ELISA Cited in Recent Boston Study

by Eagle Biosciences

EagleBio’s Intact FGF-21 ELISA
was recently utilized in Boston study by Beth Israel Deaconess Medical Center,
Harvard Medical School. This assay is the first Intact FGF-21 ELISA
assay kit that truly measures the active human intact FGF-21 (1-181) with no
cross reaction to any FGF-21 fragments.

Shenoy, V. et. al. Elevated Serum
Fibroblast Growth Factor 21 in Humans with Acute Pancreatitis. PLOS One. 2016. https://dx.doi.org/10.1371/journal.pone.0164351

Highlight from Publication:

“To assess the possibility that FGF21 is
released from the pancreas during acute injury in humans, we measured
circulating FGF21 in subjects with acute pancreatitis over the course of their
disease. We observed that acute pancreatitis subjects had significantly
increased peak circulating FGF21 values compared to healthy controls. Further,
peak FGF21 levels were observed four to six days after lipase levels peaked.
The timing of this elevation suggests that FGF21 may play a role in or be a
marker of disease recovery.” Read More

Source: (https://journals.plos.org/plosone/article?id=10.1371/journal.pone.0164351
)

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Trifluoperazine Inhibits Disordered Protein In Pancreatic Tumors

by Eagle Biosciences


A recent research study focused on screening more than 1,000 drugs already approved for various therapeutic indications. The objective was to find which drugs are capable of inhibiting the protein involved in the pancreatic cancer development process, Nupr1.

“Trifluoperazine, a molecule long used to treat anxiety has been found to interfere with the activity of a protein involved in the pancreatic cancer development process. A study by the Nanotechnology Institute of CNR, unit of Rende, in collaboration with a team of French and Spanish researchers, identified the molecule.

Pancreatic cancer is one of the most lethal tumors. Up until now, the only drugs available to fight it are generic chemotherapy treatments.”  Read More

Source: (https://reliawire.com/trifluoperazine-pancreatic-tumors/)

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EagleBio’s 25 OH Vitamin D ELISA Cited in University of Florida Study

by Eagle Biosciences


A recent
study was conducted by the University of Florida, Gainesville using
Eagle Bioscience’s 25-OH Vitamin D
ELISA from our Vitamin Assay Kit Line.
The Vitamin Assay
Kit line offered Eagle Biosciences provides unique and sensitive
assays for measuring a variety of vitamin analytes in numerous fields of
research. Check the product page for full details on our 25-OH Vitamin D
ELISA or view the links below for information about the study
referencing this kit.

Publication: 

Nelson, C. et al.  Vitamin D status of dairy cattle: Outcomes of current practices in the dairy industry. Journal of Dairy Science. December 2016, Volume 99 :12: 10150–10160. DOI: https://dx.doi.org/10.3168/jds.2016-117

“The need for vitamin D supplementation of dairy cattle has been known for the better part of the last century and is well appreciated by dairy producers and nutritionists. Whether current recommendations and practices for supplemental vitamin D are meeting the needs of dairy cattle, however, is not well known. The vitamin D status of animals is reliably indicated by the concentration of the 25-hydroxyvitamin D [25(OH)D] metabolite in serum or plasma, with a concentration of 30 ng/mL proposed as a lower threshold for sufficiency. The objective of this study was to determine the typical serum 25(OH)D concentrations of dairy cattle across various dairy operations….” Read More 

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Product Highlights: ILite® Anti-CD20 ADCC Activity Set

by Eagle Biosciences

ILite® Anti-CD20 ADCC Activity Set is for Research Use Only in the US.  Not to be used for Diagnostic Procedures.

Eagle Biosciences is proud to announce the launch of the iLite ADCC Activity Assay product line and the iLite anti-CD20 ADCC Activity Set.

Rituximab, a chimeric monoclonal antibody against CD20, was one of the first therapeutic antibodies within the oncology field to receive approval by the FDA in 1997. Ever since biosimilar and innovative biologicals with similar mechanism of action have been developed and marketed.

Antibody-dependent cell-medicated cytotoxicity (ADCC) can now, using our new iLite®ADCC Activity Assays, be measured in a straight forward, sensitive and reproducible manner.

ILite® Anti-CD20 ADCC Activity Set is a great addition to EagleBio’s Drug Monitoring kit Line which offers a unique grouping of products that provide incredible value to pre-clinical and clinical pharmacology studies, cancer research, and more specifically anti-tumor therapeutic investigation and more.

Key Advantages

The iLite® anti-CD20 ADCC Activity Set

  • Comprehensive kit– Contains 3 different genetically modified cell lines (components also available separately):
    1. Reporter Effector cell,
    2. Positive Target cell
    3. Negative Target cell
  • Fast- results in 5 hours- this set of cells enables measurements of an anti-CD20 drug’s ability to induce ADCC,
  • Easy- NO Cell culturing isrequired
  • Flexible– Effector cells, which can be used with any Target cell, include a normalization readout which can adjust for differences in cell counts.