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The Vitamin
Assay Kit line offered Eagle Biosciences provides sensitive assays for
measuring a variety of vitamin analytes.There are several publications to date for the assays in this line but
there a few new publications that we would like to highlight. Check out the
product pages for full information on the kits, or view the links below for the
new publication details.

25-OH Vitamin D ELISA Assay Kit

New Publications:

Characteristics and Outcomes of Children with Autosomal Recessive Polycystic Kidney Disease Cohort from the ESPN/ERA-EDTA Registry

Asfotase-α Improves Bone Growth, Mineralization and Strength in Mouse Models of neurofibromatosis Type-1

Vitamin B6 Whole Blood HPLC Assay Kit

New Publication:

Folate, Vitamin B12 and Vitamin B6 Status of a Group of High Socio-Economic Status Women in the Alberta Pregnancy Outcomes and Nutrition (APrON) Cohort

Eagle Biosciences Vitamin Assay Kits

Take Advantage of Our Promotion of the Month- 

on New Cardiac Biomarker Assays!

Don’t Miss Out! Hot Deals of the Month! 30% Discount on Select

Cardiac Biomarker Assays
(see below)

• BNP Fragment ELISA
• NT-proCNP ELISA
• NT-proANP ELISA
• Endostatin ELISA
• Big Endothelin-1 ELISA
• Endothelin (1-21) ELISA

View the latest information, products, and promotions from Eagle Biosciences in our Eagle i-View Newsletter. 

Highlights:

EagleBio Goes Social

Information About Our Latest Webinar- Fertility Research: What is Next?

New Contest & New Prizes

Click here to view the Eagle i-View

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The 3rd Quarter Edition is Due Out Soon! 

Fascinating Research, Exciting Announcements, Chance to Win Great Prizes!

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Bats have
always had a bad rap between their nocturnal nature and wealth of myths,
superstition, and gothic literature paints bats in mysterious and in a fearful
light. Contrary to popular myths, bats
seldom transmit disease to other animals or humans. In fact, all mammals can contract rabies but
less than 0.05% of bats that do carry rabies pose
little threat to people WHO DO NOT
HANDLE THEM. In addition, bats are
actually very important to the ecosystem, keeping insects in check and some actually acting as pollinators and seed dispersers. Bat droppings in caves are even useful
in supporting unique organisms, including bacteria useful in detoxifying
wastes, improving detergents and producing gasohol and antibiotics. Read More

So now we
have discussed how bats are important and that we should not fear them, let’s
discuss the situations in which they can be harmful. One of the greatest global health threats and
concerns is emerging diseases, which have never been seen before in humans or as with Ebola which appear sporadically
in new locations. Most emerging diseases
are zoonoses, meaning they are caused by pathogens that can jump from animals
into people. Bats host more than 65
pathogens with one of them being Ebola. Impoverished
nations have been hunting bats as a food source (bushmeat). Remember where we discussed
above that bats are not a typically a threat to those WHO DO NOT HANDLE THEM above? Read More

Image above from the www.theconversation.com.

Nashua, NH:
Eagle Biosciences is now offering unique Antibody Drug Conjugate (ADC) ELISA
Assay Kit menu including MMAE Antibody Drug Conjugate (ADC) ELISA, MMAF
Antibody Drug Conjugate (ADC) ELISA, and DM1 Antibody Drug Conjugate (ADC)
Assay ELISA. These assays will
complement and further expand their current immunology assay portfolio.

The ADC ELISA
Assay kits have excellent sensitivity, wide dynamic range, and can be used with
multiple species and sample types. These
analytes provide incredible value to pre-clinical and clinical pharmacology
studies, cancer research, and more specifically tumor marker investigation. In addition, each of these assays offer
simple procedure with quick results.

“We are
excited to bring the ADC kits to the market.” said Dan Keefe, President of
EagleBio. He continued, “These assays
will help EagleBio reach new emerging market segments in cancer research and
help us to fulfill unmet needs in the field.”

These
products are currently for research use only. Check out the list of Antibody
Drug Conjugate ELISA Assay Kits below. In addition, the antibodies used in
these kits are available for purchase upon special request.  Visit the Eagle website, or
call 866-411-8023 for full details.

MMAE Antibody Drug Conjugate (ADC) ELISA Assay Kit

MMAF Antibody Drug Conjugate (ADC) ELISA Assay Kit

DM1 Antibody Drug Conjugate (ADC) ELISA Assay Kit

C. difficile
infections are horribly uncomfortable for patients causing painful
bloating,
cramping, and excessive diarrhea. In
fact, certain strains of C. difficile cause about 250,000
hospitalizations and
14,000 deaths each year in the U.S. The quest for new types of therapy
is because of two big dilemmas with regards to antibiotic treatment.
There is increased antibiotic resistance and they
have a detrimental effect on normal gut flora which protect the body
from
harmful pathogens. So here’s the scoop…there’s now hope with ingesting poop!

Many of you
are probably thinking…ingesting stool that sounds rather disgusting but in fact
it is actually pretty brilliant! This
unique treatment has been the focus of current study at Massachusetts General Hospital
(MGH). A recent press release from the hospital describes this study’s objective to
investigate whether delivering FMT orally through capsules designed to open
upon reaching the small intestine would be just as effective as other more
invasive treatments such as delivering frozen fecal material for FMT either by
colonoscopy or nasogastric tube.

image above from:

A recent abstract pertaining to using LHCGR forms for the prediction of preeclampsia was presented at the 13th World Congress in Fetal Medicine. The World Congress is designed both for those specializing in
fetal-maternal medicine and those with a more general clinical interest
who want to be updated on developments in the field. Leading
international experts and young researchers present and discuss the
latest developments in fetal medicine. 

Objective
To explore the possible role of circulating human chorionic gonadotrophin receptor (LHCGR) forms in the prediction of early and late preeclampsia (PE) in the first trimester of pregnancy, combined with maternal baseline risk, biophysical parameters and angiogenic factors.

Methods
A case-control study, within a cohort of 5, 759 pregnancies including 20 cases of early PE, 20 of late PE (cut-off: 34 weeks at delivery), 300controls. Maternal characteristics, mean arterial pressure (MAP), uterine artery (UtA) Doppler (11-13 weeks), placental growth factor (PlGF),soluble Fms-like tyrosine kinase-1 (sFtl-1), circulating sLHCGR, and hCG-LHCGR complexes (8-11 weeks) were measured/recorded.  LHCGR difference (LHCGR-D) was calculated by subtracting hCG-LHCGR value from the corresponding sLHCGR. All parameters were normalized by logarithmic transformation, converted in MoM, and logistic regression analysis was used to predict PE.

Conclusion
Among LHCGR forms, the LHCGR-D improves substantially the prediction for early and late PE in first trimester, if used in algorithms. These new biomarkers seemed useful if used in combination (LHCGR-D) in the context of prediction of PE.

READ Entire AACC Scientific Abstract HERE