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Sfn’s 45th annual meeting is the premier venue for neuroscientists to present emerging science, learn from experts, forge collaborations with peers, explore new tools and technologies, and advance careers. As always it was quite an event this year and Eagle Biosciences was proud to be part of it!
Thank you to everyone that stopped by our booth to say hello, connect, and learn about our Neurobiology assays and other products.
Related Kits:
Adrenaline ELISA
Dopamine ELISA
Noradrenaline ELISA
Neurobiology Assay Kits
Catecholamine Assay Kits
Catecholamine Sensitive Assay Kits
Related News:
EagleBio Biomarker Spotlight: Biogenic Amines
Come Connect with EagleBio at Neuroscience 2015!
EagleBio’s Serotonin ELISA: A Rock Solid Assay and 5 Recent Citations you Should Not Miss
New Study Referencing EagleBio’s Serotonin ELISA Assay Kit
January 21, 2015- Eagle Biosciences Shares Some New Publications Across Multiple EagleBio Assay Kit Product Lines
July 5, 2012: Eagle Biosciences Introduces High Sensitive Catecholamine Assay Kits
Eagle Biosciences’ BI-CAT ELISA is a unique assay in our Neurobiology Assay Kit line with a wide dynamic range, and it provides the ability to measure both urine and plasma samples.
The Neurobiology Assay Kit line offered Eagle Biosciences provides a comprehensive array of sensitive tools to measure catecholamines, biogenic amines, and numerous neuroscience-related analytes on various types of samples. Check the product pages for full details on the kit or view the links below to find a new publications referencing our BI-CAT ELISA.
Recent Citation Utilizing EagleBio’s BI-CAT ELISA:
Study Summary:
Hypertension is one of the most common clinical disorders in the world and there is a great need to search for a therapy that offers minimal adverse effects. There is also a need for targeted approaches directed at the underlying mechanisms of hypertension.
The objective of this study was to examine effectiveness of electroacupuncture (EA) at select acupoints to reduce systolic blood pressure (SBP) and diastolic blood pressures (DBP) in hypertensive patients. Eagle Biosciences’ BI-CAT ELISA was to measure norepinephrine, and epinephrine for assessing secondary outcomes examining underlying mechanisms of acupuncture with plasma concentrations before and after 8 weeks of treatment. After
treatment, the plasma concentration of norepinephrine, which was initially elevated, was decreased by 41%;
likewise, renin was decreased by 67% and aldosterone by 22%.
This study revealed that EA at select acupoints reduces blood pressure. Sympathetic and renin-aldosterone systems were likely related to the long-lasting EA actions.
Related Kits:
Noradrenaline ELISA
Neurobiology Assay Kits
Catecholamine Assay Kits
Catecholamine Sensitive Assay Kits
Related News:
EagleBio Biomarker Spotlight: Biogenic Amines
Catecholamine Sensitive Assays: Product Highlights
EagleBio’s Serotonin ELISA: A Rock Solid Assay and 5 Recent Citations you Should Not Miss
New Study Referencing EagleBio’s Serotonin ELISA Assay Kit
Come visit us at Booth # 255!
What are Biogenic Amines?
Biogenic amines are naturally occurring biologically active compounds with a low molecular weight and with one or more amine groups. They include three classes of neurotransmitters:
- Catecholamines: Dopamine, Noradrenaline, and Adrenaline
Catecholamine is the name of a group of aromatic amines (noradrenaline, adrenaline, dopamine, and their derivatives) which act as hormones and neurotransmitters, respectively.
- Indoleamines: Serotonin and Melatonin
Indoleamines are organic compounds made up of indole groups that have an amine group on them. Indoles, as nitrogen-containing molecules are involved in many biologically active molecules. Both melatonin and serotonin are neurohormones that play significant roles in the regulation of hormonal and neurological processes and responses to environmental stimuli in a wide range of species.
- Histamine:
Histamine (β-imidazole-ethylamine), a biogenic amine, is a product of the histidine metabolism. It is produced by decarboxylation of histidine. Histamine is widely distributed in mammalian tissues and it plays a major role in the initial phase of an anaphylactic reaction. It is also involved in the regulation of physiological function in the gut and acting as a neurotransmitter.
Why Measure Biogenic Amines?
Biogenic amines are implicated in a wide range of behaviors ranging from central homeostatic functions to cognitive phenomena such as attention. It is important to measure biogenic amines because of their involvement in these significant and intricate physiological functions within the body. In fact, they can be used to study numerous health conditions and disease states such as hypertension, degenerative cardiac diseases, schizophrenia and manic-depressive psychosis. Measuring these analytes provide unique insight for assisting researchers at the forefront of neurobiology research and therapeutic drug targets.
References:
Murch, S. et al. Role of Indoleamines in Regulation of Morphogenesis in In Vitro Cultures of St. John’s wort (Hypericum perforatum L.). Can. Int. Dev. Agency (CIDA) 2004; 425-
Purves, D et al., editors. The Biogenic Amines. Neuroscience 2nd edition 2001; Available from: https://www.ncbi.nlm.nih.gov/books/NBK11035
Related Kits:
Adrenaline ELISA
Dopamine ELISA
Noradrenaline ELISA
Neurobiology Assay Kits
Catecholamine Assay Kits
Catecholamine Sensitive Assay Kits
Related News:
Catecholamine Sensitive Assays: Product Highlights
EagleBio’s Serotonin ELISA: A Rock Solid Assay and 5 Recent Citations you Should Not Miss
New Study Referencing EagleBio’s Serotonin ELISA Assay Kit
January 21, 2015- Eagle Biosciences Shares Some New Publications Across Multiple EagleBio Assay Kit Product Lines
Eagle Biosciences’ Immunology Assay Kit line is a complete group of products comprised of a unique,versatile set of products for a variety of applications, research, and fields of study surrounding overall immunological health and immunological-related disorders. Our Antibody Drug Conjugate (ADC) ELISA menu are a comprehensive set of assays which are the first commercially available quantitative ADC test in ELISA format. Each of these assays: MMAE Antibody Drug Conjugate (ADC) ELISA Assay Kit, MMAF Antibody Drug Conjugate (A DC) ELISA Assay Kit, and DM1 Antibody Drug Conjugate (ADC) ELISA Assay Kit have a variety of benefits such as excellent sensitivity and specificity. Together, these assay kits provide incredible value to pre-clinical and clinical pharmacology studies, cancer research, and more specifically antitumor therapeutic investigation.
Why Measure Antibody Drug Conjugates (ADCs) using our Assays?
Antibody-drug conjugates (ADCs) are a new type of targeted therapy for cancer treatment that bring a lot of hope to oncology-related areas. ADCs are cancer cell specific monoclonal antibodies that are conjugated with highly potent cyotoxics via a specific linker, which deliver and release the drug directly inside the tumor cell. ADCs, thus significantly increase target specificity and reduce toxicity.
Measurement of circulating specific cytotoxic ADCs are extremely important for pre-clinical and clinical studies to help discover unique, targeted, efficacious, and safer anticancer treatments.Given the variations in antibodies, drug potencies, and tumor types, there’s plenty of room for multiple novel linker technologies and techniques that offer better control for making ADCs.
The assays in Eagle Biosciences’ ADC kit menu have been developed with specific antibodies to DM1, MMAE, and MMAF and offer not only the ability to measure numerous sample types but also multiple species.
Key Advantages of EagleBio’s Antibody Drug Conjugate Assays
- Excellent sensitivity
- Simple procedure
- Wide dynamic range
- Quick results: under 3 hours
- Versatile: multiple sample types & species
Related Kits:
MMAE Antibody Drug Conjugate (ADC) ELISA Assay Kit
MMAF Antibody Drug Conjugate (A DC) ELISA Assay Kit
DM1 Antibody Drug Conjugate (ADC) ELISA Assay Kit
Immunology Assay Kits
Related News:
October 2014: Eagle Biosciences Introduces New Antibody Drug Conjugate ELISA Assays
Nashua, NH:
Eagle Biosciences is now offering a new ADMA FAST ELISA Assay Kit. This assay was
developed and manufactured by DLD Diagnostika GmbH (www.DLD-Diagnostika.de) in
Germany. DLD is a worldwide leader in niche tests for autoimmune and cardiovascular
diseases as well as renal dysfunction.
“We are
pleased to add on yet another great kit from DLD to our Cardiovascular Assay Kit line here at EagleBio.” said Dan Keefe, President of EagleBio. He added, “This assay, like the other ADMA
kits from DLD, is the gold standard in testing for cardiovascular disease risk.
It offers many advantages over other kits in the market such as excellent
specificity, sensitivity, and excellent correlation to LC-MS/MS.” Keefe
concluded, “To top it all off, this kit provides precise results in under 3
hours while most other assays require an overnight incubation.”
This product
is currently for research use. Check out the links below, visit the Eagle website, www.EagleBio.com,
or call 866-411-8023 for full details.
Related Kits:
ADMA ELISA Assay Kit
ADMA (Asymmetric Dimethylarginine) / Arginine ELISA Assay KIt
ADMA Ultrasensitive ELISA Assay Kit
Homoarginine ELISA Assay Kit
Cardiovascular Assay Kits
Related News:
EagleBio Biomarker Spotlight: ADMA
New Listing of ADMA Assay Publications
Eagle Biosciences Continues Product Line Expansion with launch of New Homoarginine ELISA kit
EagleBio’s Immunoaffinity Columns
Effective, Efficient Tools for Mycotoxin Contamination & Vitamin Analysis
Eagle Biosciences’ Immunology Assay Kit line is a complete group of products comprised of a unique,versatile set of products for a variety of applications, research, and fields of study surrounding overall immunological health and immunological-related disorders. Some of the most unique products in our Immunology Assay Kit Line are the Immunoaffinity Columns which are effective and efficient tools for assessing and measuring mycotoxin contamination and providing vitamin analysis. Individually, each of these columns: Fumonisin Immunoaffinity Column, Aflatoxin Immunoaffinity Column, Ochratoxin Immunoaffinity Column, Folic Acid Immunoaffinity Column, and Biotin Immunoaffinity Column offer a variety of advantages over other competing immunoaffinity columns such as ease of use and high-specificity. Collectively, this line offers researchers a column for every research need pertaining to food and feed analysis.
Why Measure Mycotoxins and Vitamins in Food and Feed?
Evaluation of food and feed through myotoxin and vitamin analysis is important for assessing its composition and contamination level for providing safety to those who consume them.
Mycotoxins are fungal toxins and occur either in the growth phase of plants, when storing food, and raw materials such as cereals and nuts, or they can enter the food chain as metabolites. High levels of mycotoxins can endanger humans and other vertebrates, thus continued testing should be done to ensure that these toxins remain at acceptable levels in the food.
Vitamin analysis in food also has a variety of purposes. In fact, it is used to provide quality assurance
for supplemented products; to study changes in vitamin content attributable to
food processing, packing, and storage. This type of analysis also helps to provide data for food composition tables and to check compliance with contract specifications and nutrient labeling regulation.
Key Advantages of EagleBio’s Immunoaffinity Columns line:
- Excellent flow behavior
- Incredible robustness
- Exceptional specificity
- High permeability with no increase pressure required
- Ready-to-use columns in various sizes
Related Products:
Immunology Assay Kits
Vitamin Assay Kits
Fumonisin Immunoaffinity Column
Aflatoxin Immunoaffinity Column
Ochratoxin ImmunoaffinityColumn
Folic Acid Immunoaffinity Column
Biotin Immunoaffinity Column
AOZDFT Immunoaffinity Column
Related News:
EagleBio Biomarker Spotlight: Biogenic Amines
Catecholamine Sensitive Assays: Product Highlights
EagleBio’s Serotonin ELISA: A Rock Solid Assay and 5 Recent Citations you Should Not Miss
New Study Referencing EagleBio’s Serotonin ELISA Assay Kit
January 21, 2015- Eagle Biosciences Shares Some New Publications Across Multiple EagleBio Assay Kit Product Lines
July 5, 2012: Eagle Biosciences Introduces High Sensitive Catecholamine Assay Kits
Related Kits:
Adrenaline ELISA
Dopamine ELISA
Noradrenaline ELISA
Serotonin ELISA Assay
Kit
Neurobiology Assay Kits
Catecholamine Assay Kits
Catecholamine Sensitive Assay Kits
An interesting study was just recently published in the Journal of Human Anatomy and Physiology Society utilizing EagleBio’s Ultrasensitive Cortisol Saliva ELISA. Our Ultrasensitive Cortisol Saliva ELISA is part of our Steroid Assay Kit Line which offers an array of interesting and sensitive assays for different hormone analytes and research needs. Check the product page for full details on the kit or view the links below to find a new publication referencing our Ultrasensitive Cortisol Saliva ELISA.
Publication:
An undergraduate physiology lab module was developed to enhance student understanding of the functions
of cortisol hormone, the circadian rhythm associated with cortisol release, proper ELISA technique, and
quantitative data analysis methods including linear regression and t-test assessment. Eagle Biosciences’ Ultrasensitive Cortisol Saliva ELISA was used to measure cortisol levels in the saliva of a cohort of students. Researchers concluded that human cortisol
levels are significantly different between morning
and evening as they clearly observed the very robust nature of fluctuating cortisol levels in circadian rhythm.
Related Kits:
Steroid Assay Kits
Cortisol ELISA Assay Kit
Cortisol Saliva ELISA Assay Kit
Testosterone ELISA Assay Kit
Testosterone Saliva ELISA Assay Kit
Related News:
Eagle Biosciences Shares New Literature Utilizing Select Hormone Assays
Biomarker Spotlight: ACTH (Adrenocorticotropic Hormone
April 1, 2011: Eagle Biosciences Introduces High Sensitive Steroid Saliva ELISA Kits