Eagle Biosciences proudly offers a broad range of products in our extensive catalog. In addition to the well known ELISA format, we offer several assay kits in a Chemiluminescent Enzyme Immunoassay (CLEIA) format.


ELISAs use antibodies to detect the presence of a protein in a liquid sample. In the most common form, antigens are applied to a stable surface (usually a microtiter plate). Then the corresponding antibody, linked with an enzyme, is added to form a complex. Finally, the enzyme’s substrate is added, which produces a measurable reaction, usually in the form of a color change.

CLEIAs also utilize antibody-enzyme reactions, but offer a higher level of sensitivity due use of chemiluminescence rather than colorimetric absorbance or fluorescence. Chemiluminescence allows detection of trace amounts of analytes because samples typically have little to no background interference. These reactions are also easily measured using a photomultiplier or photodiode. These types of kits are increasing in popularity due to their increased sensitivity, specificity, reliability, and reproducibility.

Our available CLEIA/CLIA kits

GFAP (Glial Fibrillary Acidic Protein) CLIA Assay Kit
MedFrontier FGF23 (Human Intact FGF23) CLEIA ELISA Assay

Contact us if you are looking for a specific CLEIA or if you have questions about any of our products.

Glial Fibrillary Acidic Protein (GFAP) is a monomeric intermediate protein found in the astroglial cells of the Central Nervous System. Astroglial cells are found in the white and gray matter of the brain. GFAP and other intermediate filaments provide support and nourishment for cells in the brain and spinal cord.

Why is GFAP Important?

Astroglial cells produce GFAP when an injury or trauma damages the cells of the central nervous system. Glial Fibrillary Acidic Protein (GFAP) is a promising research brain-specific glial-derived biomarker for TBI (traumatic brain injury) in adults and children. Studies have demonstrated that GFAP is released into serum following a TBI within an hour of injury and remains elevated for several days after injury. All indications are the GFAP is an interesting biomarker for indication of a TBI and retinal stress.

Eagle Biosciences offers the most sensitive assays available worldwide in simple-to-use ELISA and Chemiluminescence formats for detecting GFAP:

Contact us to talk about how we can help with an evaluation GFAP ELISA or GFAP CLIA assays.