Human Des [1-6] IGF-II

$170.00

The Eagle Biosciences Human Des [1-6] IGF-II is for research use only and not to be used for diagnostic procedures.

SKU: MU100 Categories: ,

Human Des [1-6] IGF-II

The Eagle Bioscience’s Human Des [1-6] IGF-II is for research use only and not to be used for diagnostic procedures.


Product Specifications

Source:

Produced in E.coli. 

Description:

Human Des [1-6] insulin-like Growth Factor-II is a 61 amino acid analogue of human IGF-II lacking the N-terminal hexapeptide Ala-Tyr-Arg-Pro-Ser-Glu. This reagent is more potent than IGF-II in vitro and in vivo. This increased potency is due to reduced binding of human Des [1-6] IGF-II to most of the IGF binding proteins which modify the biological actions of IGF-II. This reagent binds to both the type 1 and type 2 IGF receptors with similar affinity to wild type IGF-II. This is a high quality research reagent for use in studies on cell growth, IGF receptors and IGF binding proteins.

  • Quantity: 100 µg
  • Molecular Weight: 6765 daltons
  • Purity: >95 % (by HPLC analysis)
  • N-terminal Sequence: Analysis of 7 residues
  • Biological Activity: Stimulation of protein synthesis in rat L6 myoblasts (ED50 <75 ng/ml) IGF type 1 receptor binding assay (ED50 < 50 ng/ml), IGF type 2 receptor binding assay (ED50 < 100 ng/ml), IGF binding protein assay: ED50 > 1000 ng/ml)
  • Appearance: White powder freeze-dried from 0.1M acetic acid and stored under nitrogen at a slight vacuum.
  • Endotoxin: < 0.1 EU/μg
  • Storage/Stability: At least 2 years at 2 – 8°C (as a freeze dried product)

Related Products

Human [Arg6] IGF-II
Human [Arg3] IGF-I (Media Grade)
Human Des [1-3] IGF-I


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Package Inserts

Product Manual


Please note: All documents above are for reference use only and should not be used in place of the documents included with this physical product. If digital copies are needed, please contact us.

Product Citations