Human [Arg6] IGF-II

$170.00

The Eagle Bioscience’s Human [Arg6] IGF-II is for research use only and not to be used in diagnostic procedures.

SKU: GU020 Categories: ,

Human [Arg6] IGF-II

The Eagle Bioscience’s Human [Arg6] IGF-II is for research use only and not to be used for diagnostic procedures.


Product Specifications

Source:

IGF-II is produced in E.coli using a patented expression system.

Description:

Human [Arg6] insulin-like Growth Factor-II is an analogue of human IGF-II which has an Arginine substitution in place of Glutamic acid at position 6 of the Human insulin-like Growth Factor-II sequence. [Arg6] IGF-II exhibits reduced affinity for IGF binding proteins (IGFBPs) compared with human IGF-II and has a slightly greater affinity than Des [1-6] IGF-II for the type 2 IGF receptor. 

  • Purity: >95 % (as determined by HPLC analysis)
  • Quantity: 20 µg
  • Molecular Weight: 7469 daltons – this has been confirmed by Mass Spectrometry
  • N-terminal sequence analysis of recombinant product: Analysis of 7 residues
  • Biological Activity: Stimulation of protein synthesis in rat L6 myoblasts (ED50 <100 ng/ml) IGF type 2 receptor binding assay (ED50 < 100 ng/ml) IGF binding protein assay: ED50 > 1000 ng/ml)
  • Endotoxin (LAL): <0.1 EU/ug
  • Storage/Stability: At least 2 years at 2-4°C (lyophilized)
  • Appearance: White Powder
  • State: Dried from 0.1 M acetic acid under dry nitrogen at a slight vacuum (-25kPa)

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Package Inserts


Please note: All documents above are for reference use only and should not be used in place of the documents included with this physical product. If digital copies are needed, please contact us.

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