Human Des [1-6] IGF-II

$240.00

Human Des [1–6] insulin-like growth factor-II (IGF-II) is a 61–amino acid analogue of human IGF-II lacking the N-terminal hexapeptide (Ala-Tyr-Arg-Pro-Ser-Glu). More potent than IGF-II in vitro and in vivo, its enhanced activity results from reduced binding to IGF binding proteins. Retains similar affinity for type 1 and type 2 IGF receptors. Ideal for studies on cell growth, IGF receptors, and binding proteins. This product is for research use only and not to be used in diagnostic procedures.

SKU: MU100 Category: Proteins & Antibodies Tags: Antibodies & Proteins, Growth Factors, Reagents

Description

Human Des [1-6] IGF-II

Human Des [1-6] insulin-like Growth Factor-II (IGF-II) is a 61 amino acid analogue of human IGF-II lacking the N-terminal hexapeptide Ala-Tyr-Arg-Pro-Ser-Glu. Human Des [1-6] IGF-II is more potent than IGF-II in vitro and in vivo. This increased potency is due to reduced binding of human Des [1-6] IGF-II to most of the IGF binding proteins which modify the biological actions of IGF-II. Human Des [1-6] IGF-II binds to both the type 1 and type 2 IGF receptors with similar affinity to wild type IGF-II. This is a high quality research reagent for use in studies on cell growth, IGF receptors and IGF binding proteins.

This Human Des [1-6] IGF-II is manufactured in Australia by GroPep Bioreagents.


Size	100 µg

Sensitivity

Dynamic Range

Incubation Time

Sample Type

Storage	2-8°C

Alternative Names	Human Des [1-6] insulin-like Growth Factor-II (IGF-II)

Product Citations

Human Des [1-6] IGF-II$240.00