Human Des [1-6] IGF-II

Human Des [1-6] IGF-II

$190.00

Human Des [1–6] insulin-like growth factor-II (IGF-II) is a 61–amino acid analogue of human IGF-II lacking the N-terminal hexapeptide (Ala-Tyr-Arg-Pro-Ser-Glu). More potent than IGF-II in vitro and in vivo, its enhanced activity results from reduced binding to IGF binding proteins. Retains similar affinity for type 1 and type 2 IGF receptors. Ideal for studies on cell growth, IGF receptors, and binding proteins. This product is for research use only and not to be used in diagnostic procedures.

SKU: MU100 Category: Tags: , ,

Human Des [1-6] insulin-like Growth Factor-II (IGF-II) is a 61 amino acid analogue of human IGF-II lacking the N-terminal hexapeptide Ala-Tyr-Arg-Pro-Ser-Glu. Human Des [1-6] IGF-II is more potent than IGF-II in vitro and in vivo. This increased potency is due to reduced binding of human Des [1-6] IGF-II to most of the IGF binding proteins which modify the biological actions of IGF-II. Human Des [1-6] IGF-II binds to both the type 1 and type 2 IGF receptors with similar affinity to wild type IGF-II. This is a high quality research reagent for use in studies on cell growth, IGF receptors and IGF binding proteins.

This product is manufactured in Australia by GroPep Bioreagents.

Size 100 µg
Source Species Recombinant
Expression System Ecoli
Storage 2-8°C
Alternative Names Human Des [1-6] insulin-like Growth Factor-II (IGF-II)

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