Tag: Intact FGF23 ELISA

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Eagle Biosciences Will Be at ASN Kidney Week 2019

by Eagle Biosciences

Eagle Biosciences will be at ASN Kidney Week in Washington, DC!

ASN Kidney Week is this week, Thursday, November 7 to Sunday, November 10, at the Walter E. Washington Convention Center. Stop by booth #2005 to learn more about Vanin-1, Klotho, Intact FGF23 and other assays that could help you with your kidney related research! We’ll be there to answer any questions you may have, or stop and say hi! We love seeing our customers!

Product Highlights

Vanin-1: Eagle Bio has two new Vanin-1 ELISA Kits. Vanin-1 is an early biomarker of renal tubular damage in drug-induced acute kidney injury, obstructive nephropathy, and diabetic nephropathy.

FluoBolt Klotho: This newest addition to our FluoBolt line of fluorescence immunoassays allows for highly sensitive measurement of Klotho, a critical biomarker for chronic kidney disease and failure, renal- and hepatocellular carcinomas, osteoporosis or cardiovascular diseases.

Intact FGF23: This CLEIA ELISA is a unique and highly accurate assay for the measurement of FGF23, which has been linked to impaired renal function.

Contact us for more information about these products.

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Eagle Biosciences Human Intact FGF23 CLEIA ELISA Used in Diabetes Study

by Eagle Biosciences

The Eagle Biosciences MedFrontier FGF23 (Human Intact FGF23) CLEIA ELISA Assay was used in a recently published study looking at the association between FGF23 levels and major adverse cardiovascular events (MACE) and mortality in patients with type 2 diabetes and normal or mildly impaired kidney function.

FGF23 is an endocrine hormone involved in vitamin D metabolism and phosphorous level regulation. Previous studies have shown a link between insulin resistance and an increase in FGF23, which researchers believe affects renal phosphorous handling and leads to a higher risk of MACE.

The study did find evidence of a connection with FGF23 levels and an increased risk of MACE or mortality in participating patients.

Read more about this study here.

Contact us for more information about this kit.

Study Citation:
Fibroblast Growth Factor 23 and Mortality in Patients With Type 2 Diabetes and Normal or Mildly Impaired Kidney Function
Stanley M.H. Yeung, S. Heleen Binnenmars, Christina M. Gant, Gerjan Navis, Ron T. Gansevoort, Stephan J.L. Bakker, Martin H. de Borst, Gozewijn D. Laverman
Diabetes Care Sep 2019, dc190528; DOI: 10.2337/dc19-0528

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Intact FGF23 ELISA Kit Is Here!

by Eagle Biosciences

We at Eagle Biosciences, Inc are Proud to Announce an Exclusive Partnership with Kyowa Medex Co., Ltd from Tokyo, Japan!


 

MedFrontier FGF-23 provides a simpler and quicker assay procedure that yields a broader dynamic range than it’s competitors 

 

About the NEW MedFrontier FGF23 ELISA Kit…

MedFrontier FGF-23 is a sandwich ELISA kit that measures only intact/active forms of FGF23. Manufactured by Kyowa Medex Co. of Tokyo, Japan, the MedFrontier FGF23 is the only kit of its kind. Studying intact FGF23 has shown to provide greater accuracy when researching the importance of this protein.

Dynamic Range 15-3000 pg/mL
Incubation Time ~2 hours
Sample Size 20 µL
Sample Type Serum

What is FGF23?

Fibroblastic Growth Factor 23 (FGF23) is a hormone that is secreted by osteoblasts with the bones. This protein works primarily with the kidneys to help regulate levels of phosphate within the bloodstream via signals for removal or reabsorbtion. The parathyroid and digestive system also aid in phosphates homeostasis within the body. The kidneys remove excess phosphate through waste, and reabsorbs it via the small intestines when needed.

Why Measure FGF23?

Phosphate plays a critical role in the formation and growth of bones in children and maintaining strength in adults. If there is an imbalance of FGF23 within the bloodstream, it can cause hyper- and hypophosphatemia. These conditions have been linked to Rickets, osteomalacia, and impaired renal function to name a few.