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IGFBP-6 ELISA by EagleBio

Product Highlights: IGFBP-6 ELISA

IGFBP-6 ELISA is for Research Use Only

Eagle
Biosciences’ Endocrine Assay Kit Line that consists of a comprehensive
product grouping of unique and sensitive assays for measuring a variety of
analytes for diabetes and obesity research. Our IGFBP-6 ELISA is one of the exceptional assays in this Endocrine Assay Kit Line that offers a reliable method for
measuring IGFBP-6 concentrations in serum, plasma and cell culture
supernatants.

Why Measure IGFBP-6?

Insulin-like
Growth Factor Binding protein 6 (IGFBP-6) has been identified to be a selective
inhibitor of IGF-II activities such as proliferation, survival and
differentiation of cells. According to a recent publication, Bach, L. this marker
has been shown to have a number of IGF-independent actions, involving promotion
of apoptosis in some cells and inhibition of angiogenesis. It is because of these roles that IGFBP-6
should be studied further in various fields of research[1].

EagleBio’s IGFBP-6 ELISA allows secure and reproducible measurement of IGFBP-6 in
human body fluids and is a suitable tool for the study of IGFBP-6 in growth,
cancer and bone metabolism.

Key Advantages of EagleBio’s IGFBP-6
ELISA:

Excellent specificity
High sensitivity
Wide dynamic Range
Small sample size

References:

1.Bach, L. Recent insights into the actions of IGFBP-6 J Cell Commun Signal 2015: 9(2): 189–200.https://www.ncbi.nlm.nih.gov/pmc/articles/PMC4458248/

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IGF-1 ELISA

IGFBP-4
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IGFBP-3 ELISA

IGFBP-3
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IGFBP-2 ELISA ASSAY KIT

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Study: Obesity Surgery May Cure Diabetes

by Eagle Biosciences

A new study gives the strongest evidence yet that obesity surgery can cure diabetes. Patients who had surgery to reduce the size of their stomachs were five times more likely to see their diabetes disappear over the next two years than were patients who had standard diabetes care, according to Australian researchers.

(source: https://www.foxnews.com/story/2008/01/23/study-obesity-surgery-may-cure-diabetes.html)

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EagleBio’s Immunoaffinity Columns: Product Highlights

by Eagle Biosciences

EagleBio’s Immunoaffinity Columns

Effective, Efficient Tools for Mycotoxin Contamination & Vitamin Analysis

Eagle Biosciences’ Immunology Assay Kit line is a complete group of products comprised of a unique,versatile set of products for a variety of applications, research, and fields of study surrounding overall immunological health and immunological-related disorders. Some of the most unique products in our Immunology Assay Kit Line are the Immunoaffinity Columns which are effective and efficient tools for assessing and measuring mycotoxin contamination and providing vitamin analysis. Individually, each of these columns: Fumonisin Immunoaffinity Column, Aflatoxin Immunoaffinity Column, Ochratoxin Immunoaffinity Column, Folic Acid Immunoaffinity Column, and Biotin Immunoaffinity Column offer a variety of advantages over other competing immunoaffinity columns such as ease of use and high-specificity. Collectively, this line offers researchers a column for every research need pertaining to food and feed analysis.

Why Measure Mycotoxins and Vitamins in Food and Feed?

Evaluation of food and feed through myotoxin and vitamin analysis is important for assessing its composition and contamination level for providing safety to those who consume them.

Mycotoxins are fungal toxins and occur either in the growth phase of plants, when storing food, and raw materials such as cereals and nuts, or they can enter the food chain as metabolites. High levels of mycotoxins can endanger humans and other vertebrates, thus continued testing should be done to ensure that these toxins remain at acceptable levels in the food.

Vitamin analysis in food also has a variety of purposes. In fact, it is used to provide quality assurance
for supplemented products; to study changes in vitamin content attributable to
food processing, packing, and storage. This type of analysis also helps to provide data for food composition tables and to check compliance with contract specifications and nutrient labeling regulation.

Key Advantages of EagleBio’s Immunoaffinity Columns line:

Excellent flow behavior
Incredible robustness
Exceptional specificity
High permeability with no increase pressure required
Ready-to-use columns in various sizes

Related Products:

Immunology Assay Kits

Vitamin Assay Kits

Fumonisin Immunoaffinity Column

Aflatoxin Immunoaffinity Column

Ochratoxin ImmunoaffinityColumn

Folic Acid Immunoaffinity Column

Biotin Immunoaffinity Column

AOZDFT Immunoaffinity Column

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Recent Publication in Sci Signal Citing EagleBio’s Biotin ELISA

by Eagle Biosciences

The Vitamin Assay Kit line offered Eagle Biosciences provides unique and sensitive assays for measuring a variety of vitamin analytes. Our Biotin ELISA Assay Kit is a top-notch assay that provides a method that is easy to use, cost effective, and provides quantifiable results in under 3 hours. This kit has proven to be a valuable tool to researchers in various fields of study.

There is one recent study described below utilizing our Biotin ELISA Assay Kit, designed for the quantitative determination of Biotin (Vitamin H, Coenzyme R, Vitamin B7) in food products, cell culture, and tissue samples.

Publication:

Binding of the sphingolipid S1P to hTERT stabilizes telomerase at the nuclear periphery by allosterically mimicking protein phosphorylation

Study Summary:

In normal adult cells, the structure at the ends of chromosomes, called the telomere, becomes progressively shorter with each replication cycle. When telomeres get too short or damaged, the cell stops dividing and becomes senescent. The enzyme telomerase maintains the integrity of telomeres, and phosphorylation stabilizes the catalytic subunit (called TERT) of this enzyme. In both normal fibroblasts and lung cancer cells, Panneer Selvam et al. found that binding of the phospholipid S1P to TERT mimicked protein phosphorylation and prevented TERT degration. Disrupting the interaction between S1P and TERT by either depleting S1P or mutating the interaction site in TERT impaired telomere maintenance and promoted senescence in cultured cells and decreased the growth of lung cancer cell xenografts in mice. Researchers utilized Eagle Biosciences’Biotin ELISA Assay Kit to measure levels of Biotin in Biotinylated S1P–bound hTERT proteins.

Related Products:

Vitamin Assay Kits

Vitamin Control Sets

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New Publications for Select Vitamin Assays Kits

EagleBio’s 25-OH Vitamin D ELISA: Product Highlights

May 15, 2014: Eagle Biosciences Adds to Vitamin Assay Menu

10 Reasons to Keep Up with Your Vitamin D Levels

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New Study Utilizing EagleBio’s Human Adiponectin ELISA Assay Kit

by Eagle Biosciences

EagleBio is pleased to share a recent publication below referencing the use of our Human Adiponectin ELISA Assay Kit. This Adiponectin ELISA Kit is a quick, simple, and sensitive assay for the quantitative determination of human adiponectin in human serum and plasma. This assay is a part of our Endocrine Assay Kit Line, a line that offers a comprehensive product grouping of unique and for measuring a variety of analytes for diabetes and obesity research.

Publication Citing EagleBio’s Human Adiponectin ELISA Assay Kit:

Effect of coenzyme Q10 on glycaemic control, oxidative stress and adiponectin in type 2 diabetes

Summary:

This study was planned to investigate the effect of coenzyme Q10 (CoQ10) supplementation on glycaemic control, oxidative stress (OS), and adiponectin levels in type 2 diabetic (T2DM) patients. It is the first study on diabetic patients focused on evaluating the effect of CoQ10 on adiponectin levels.

In conclusion, after eight weeks of supplementation with CoQ10 , it may reduce OS in T2DM patients but it may not change glycaemic control and adiponectin levels. In order to confirm this effect, further investigations with larger populations and longer periods are required.

Related Kits:

Human Adiponectin ELISA Assay Kit

Mouse Adiponectin ELISA Assay Kit

Rat Adiponectin ELISA Assay Kit

Resistin ELISA Assay Kit

Endocrine Assay Kits

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EagleBio’s FGF23 (C-terminal) ELISA: Product Highlights

by Eagle Biosciences

Measuring Both Intact and C-Terminal Fragments with Versatility and High Sensitivity.

FGF-23 (C-Terminal) ELISA is for Research Use Only, Not to be used for diagnostic procedures.

Eagle Biosciences’ Bone Metabolism Line is a comprehensive portfolio of assays for detecting and monitoring numerous biomarkers for the regulation of bone and mineral homeostasis, assisting researchers in various fields of study. One unique kit offered in our Bone Metabolism Line is our FGF23 (C-Terminal) ELISA which offers highly sensitivity, versatility with use of multiple sample types with excellent stability, and valuable results in emerging areas of research. Our FGF23 (C-Terminal) ELISA assay provides incredible value and unique insights for research surrounding the investigation new biomarkers that could improve prediction of CKD progression, as well as the discovery of new drug targets.

Why Measure FGF23 with EagleBio’s Assay?

Highly Sensitive: clear differentiation even at low serum FGF23 levels
Multi-Matrix Samples: serum and plasma samples (EDTA, heparin, citrate)
Serum Based Standards and Controls: provides biologically reliable data
Small Sample Volume: only 50 µl of sample required
Simple Assay: easy protocol, all reagents are included, and easily adapted for automation

EagleBio’s FGF23 ELISA is the most specific kit in the market, uniquely

designed to detect both Intact and C-Terminal fragments.

Related Kits:

FGF23 ELISA

Bone Metabolism Assay Kits

Related News:

January 2015: Eagle Biosciences Introduces New FGF23 (C-Terminal) ELISA
Assay