Human Insulin-like growth factor binding protein-5 (IGFBP-5) is a 252 amino acid protein which is a member of a family of six circulating proteins that bind IGF-I and IGF-II with high affinity and modulate their metabolic and mitogenic effects. Human IGFBP-5 preferentially binds to IGF-II and primarily inhibits the effects of IGF peptides. It can also form a ternary complex with the acid-labile sub-unit. It binds to extra-cellular matrix proteins which protect it from proteolysis and modify its biological functions. IGFBP-5 may also elicit a biological action through a non-IGF binding mechanism.
This product is manufactured in Australia by GroPep Bioreagents.
| Size | 20 µg |
| Source Species | Recombinant |
| Expression System | Mammalian |
| Storage | 2-8°C |
| Alternative Names | Human Insulin-like Growth Factor Binding Protein-5 (IGFBP-5) |