Human GFRa-1 Chicken Polyclonal Antibody
The Human GFRa-1 Chicken Polyclonal Antibody is For Research Use Only
Immunogen: Human GFRa-1
Uniprot ID: P56159
Alternative Names: RET ligand 1, TGF-beta related neurotrophic factor receptor 1
Clonality: Chicken polyclonal
Reactivity: Human GFRa-1 doesn’t cross-react with hGFRa-2, hGFRa-3, hGFRa-4
Application: ELISA, WB, IF
Purification: GFRa-1 affinity purified
Buffer: Concentrated ammonium sulphate in PBS pH 7.4
Concentration: 1 mg/ml
Unit Size: 100 µg
Related Products: Mono- and polyclonal antibodies to human growth factors and neural growth factor receptors.
Shipping: This product is shipped in non-frozen liquid form in ambient conditions.
Storage: Store at +4°C upon receipt. As product is (NH4)2SO4 precipitate, mix well by pipetting or vortexing prior use
Protocol: Western immunoblotting, recommended dilution 1:5 000 to 1:10 000; ELISA: 1:80 000 to 160 000, IF 1:1000 to 1:2000. Polyclonal antibody working titer has to be established practically for each particular antigen and assay format.
Background: Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The GFRa-1 is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol (GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor (www.ncbi.nlm.nih.gov/gene/2674).
Product Developed and Manufactured by Icosagen