HCC-REAAD ErbB3 (HER3) ELISA Assay
The HCC-REAAD ErbB3 (HER3) ELISA Assay is For Research Use Only
Size: 1×96 wells
Sensitivity: 0.3 RU
Standard Range: 0.3-0.7 RU
Incubation Time: 1.75 hours
Sample Type: Serum, plasma
Sample Size: 100 µl
Alternative Names: Hepatocellular Carcinoma -Recombinant Antigen-Antibody Detection, Receptor tyrosine-protein kinase erbB-3, HER3, Human Epidermal Growth Factor Receptor 3
Controls Included
Assay Background
Liver Cancer is the sixth most common cancer malignancy in the world with 83% of cases occurring in less developed countries [1]. Liver Cancer is the second leading cause of cancer death worldwide. The highest estimated mortality rates are in Eastern and South-Eastern Asia [1,3]. Hepatocellular Carcinoma (HCC) is the most common type of liver cancer, accounting for at least 70% of the total liver cancer cases [3]. HCC was once prevalent only in Southeast Asia and Africa due to dietary intake of aflatoxin contaminated food grains. However, in recent years, an increase of HCC incidences is discovered in Europe and United States [4]. Higher levels of ERBB3 proteins were detected in patients with HCC as compared to non-HCC patients [2].
HCC-REAAD™ ERBB3 (HER3) ELISA Assay Kit uses two layers of antibodies (i.e. capture and detection antibody) targeting at two different antigenic epitopes expressed by human ERBB3 protein capable of binding to the respective antibody to semi-quantify the level of human ERBB3 protein. The test uses an arbitrary unit of measurement known as REAAD™-units (RU).
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Product manufactured by Restalyst.