GC-REAAD™ ITIH3 ELISA Assay
The GC-REAAD™ ITIH3 ELISA Assay is For Research Use Only
Size: 1×96 wells
Sensitivity: 0.4 RU
Standard Range: 0.4-0.7 RU
Incubation Time: 1.25 hours
Sample Type: Serum, plasma
Sample Size: 100 µl
Alternative Names: Inter-alpha-trypsin inhibitor heavy chain 3, ITIH3 Protein, Human ITIH3, hITIH3, Gastric Carcinoma REAAD
Gastric Carcinoma (GC) is the fifth most common cancer malignancy in the world with more than 70% of cases occur in developing countries, and half the world total occurs in Eastern Asia [3,5,6]. GC is the third leading cause of cancer death worldwide. The highest estimated mortality rates are in Eastern Asia. High mortality rates are also present in Central and Eastern Europe, and in Central and South America. The level of ITIH3 proteins has been found to be closely associated with Gastric Carcinoma. Higher levels of ITIH3 proteins were detected in plasma with gastric carcinoma (both early and late) as compared to plasma of non-carcinoma samples [1,2,4].
GC-REAAD™ sandwich ELISA uses two layers of antibodies (i.e. capture and detection antibody) targeting at two different antigenic epitopes expressed by human ITIH3 proteins capable of binding to the respective antibody to semi-quantify the level of human ITIH3 protein. The test uses an arbitrary unit of measurement known as REAAD™-units (RU). GC-REAAD™ is useful for the semi-quantification of human ITIH3 proteins in samples.
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Product manufactured by Restalyst.