Anthranilic Acid Monoclonal Antibody


The Anthranilic Acid Monoclonal Antibody was validated for immunohistochemistry (IHC) in human brain tissues. Highly specific, as demonstrated by competitive ELISA, the antibody consistently delivered clean and reproducible stainings.

SKU: IS013 Categories: ,

Anthranilic Acid Monoclonal Antibody

The Anthranilic Acid Monoclonal Antibody is For Research Use Only

Synonyms:2-AA antibody, Anti-vitamin L1 antibody, Anti-Anthranilate antibody, Anthranilate antibody, 2-Aminobenzoic acid antibody

Immunogen: Conjugated Anthranilic acid

Isotype: IgG1 k chain

Clone: Clone 10G1-F1

Specificity: When tested in competitive ELISA, the anti-anthranilic antibody did not show any significant cross reactivity with 3-hydroxyAnthranilic acid.

Size: 0.5 mg/mL

Storage: 4°C
Storage buffer: Before use, vial should be resuspended in 50 µL of ultrapure water. Store at +4°C for short term (1-2 weeks). Aliquot and store at -20°C for long term. Avoid repeated freeze / thaw cycles

Affinity & Specificity:
Competitive ELISA demonstrates that low amounts of Anthranilic acid conjugate are required to abolish antigen-antibody reaction (high affinity), while rising concentrations of 3-OH-Anthranilic acid conjugate do not affect reaction (high specificity).
Anthranilic acid: Tryptophan catabolism along the kynurenine pathway has been extensively investigated over the past decades for its roles in immune regulation and neurotransmission. Anthranilic acid is synthesized directly from L-kynurenine, to produce 3-hydroxyanthranilic acid without generation of neurotoxic 3-OH-Kynurenine. Recently, Anthranilic acid has been described in organismal death of C.elegans, as well as in pathogen Pseudomonas aeruginosa’s tryptophan catabolism.


Immunohistochemistry (IHC): Dilute at 1:50-1:500. Perform heat antigen retrieval (pH=6) before initiating IHC staining protocol on paraffin-embedded and frozen sections
Immunofluorescence (IF): Dilute at 1:50-1:500 on paraffin-embedded and frozen sections. Perform heat antigen retrieval and incubate with incubate with fluorescent secondary antibody conjugate

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