Eagle Biosciences Lipid Peroxidase Assay Kit was recently highlighted in two studies involving hepatic ischemia and reperfusion injuries. Hepatic ischemia is a condition where the liver does not recieve enough blood or oxygen, causing the liver cells injury. Lipid peroxidation is a well-established mechanism of cellular injury, and is used as an indicator of oxidative stress in cells and tissues. Lipid peroxides are unstable and decompose to form a complex series of compounds including reactive carbonyl compounds. Polyunsaturated fatty acid peroxides generate malondialdehyde (MDA) and 4-hydroxyalkenals (HAE) upon decomposition. The measurement of these biomolecules has been used as a indicator of lipid peroxidase.
The Eagle Biosciences’ Lipid Peroxidase Assay Kit is a highly sensitive tool for measuring MDA and HAE in biological fluids.
Read more about these studies below:
Mohamed DZ, El-Sisi AE, Sokar SS, et al. Targeting Autophagy to Modulate Hepatic Ischemia/Reperfusion Injury: A Comparative Study Between Octreotide and Melatonin as Autophagy Modulators Through AMPK/PI3k/AKT/mTOR/ULK1 and Keap1/Nrf2 Signaling Pathways in Rats. Eur J Pharmacol. 2021;897:173920.