Introducing the FGF-19 ELISA Assay Kit and the Mouse FGF-21 ELISA Kit. These kits are an extension of an expansive FGF Assay line of kits Eagle Biosciences already offers. Fibroblast Growth Factors are a family of cell signaling proteins that are involved in a wide variety of biological processes. FGF-19 and FGF-21 belong to a subfamily of these proteins that function as an important role in nutrient metabolism.

More about FGF-19:

The primary source of endocrine FGF-19 is the ileum, bile acids release into the intestine after a meal to induce expression of FGF-19. Circulating FGF-19 plays an important role in maintaining proper bile acid homeostasis. Several pharmacologic studies in hyperglycemic, obese animal models have shown that FGF-19 can improve metabolic rate and lower serum glucose and hepatic triglyceride and cholesterol levels. Like insulin, FGF-19 functions as postprandial hormone to govern hepatic protein synthesis, glycogen synthesis and gluconeogenesis, but does not stimulate lipogenesis.

More about FGF-21:

FGF-21 has been implicated in the regulation of lipid and glucose metabolism under fasting and ketotic conditions. In murine models, FGF-21 is predominantly expressed in liver, but it also expressed in adipose tissue and pancreatic β-cells. FGF-21 stimulates glucose uptake in adipocytes. It also protects animals from diet-induced obesity when overexpressed in transgenic mice and lowers blood glucose and triglyceride levels when administered to diabetic rodents. When administered daily for 6 weeks to diabetic rhesus monkeys, FGF-21 caused a dramatic decline in fasting plasma glucose, fructosamine, triglycerides, insulin, and glucagon. Furthermore, elevated plasma FGF-21 concentrations in humans appear to be related to the presence of hepatic and peripheral insulin resistance.

Related Products:

FGF-23 C-Terminal ELISA Kit

MedFrontier Intact FGF-23 Assay

FGF Basic ELISA Assay

Intact FGF-21 ELISA Kit

Total FGF-21 ELISA Assay

cTerminal FGF-21 ELISA Kit

N-Terminal FGF-21 ELISA Kit

iLite FGF-21 Assay Ready Cells

If you are looking for any other specific related products or if you have questions about our offerings, contacts us here.

iLite® FGF-21 Activity Assays

First products available NOW, many more coming soon!

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iLite® FGF-21 Assay Ready Cells

The iLite® FGF21 Assay Ready Cells can be used in an assay for the quantification of the potency of analogues of human FGF21, the potency of FGFR1c antagonists or a neutralizing antibody response against such products in human serum in the absence of serum matrix effects.

Developed by:

Key benefits of iLite® FGF-21 Assay Ready Cells:

  • Unparalleled sensitivity (>10 fold inductions)
  • Highly specific reporter gene cell lines
  • Normalization read-out included
  • Negative control available for screening of unspecific activity
  • Easy to use – ready-to-use from the freezer, without culturing of cells

LIMITED OFFER!

50% off on your first iLite® FGF-21 Assay Ready Cells
Use Code: ADCC50 

 

 

30% Discount on EagleBio’s: FGF-21 ELISA

Use Promotional Code: FGF0130

Reasons to Measure FGF-21:

FGF-21 is a novel protein that has been identified as a useful biomarker for studying metabolic syndrome. Further research is needed for this analyte in order to better understand its precise pathophysiological role and its associated molecular pathways. Measuring FGF-21 may provide valuable insight for researchers in detecting, monitoring, and studying drug targets for a variety of individuals with various metabolic pathologies.

FGF-21 ELISA is for Research Use Only. 

 

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Related Kits:

FGF-21 ELISA

Endocrine Assay Kits

Related News:

Biomarker Spotlight: FGF-21