The clouded lens of a cataract in human eye. Photo courtesy of Wikimedia

Approach may have broad therapeutic implications on tissue and organ repair

Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses. Read more


(Source: https://ucsdnews.ucsd.edu/)

 

Anibody

 

Mouse Monoclonal Antibody to S-Adenosylmethionine (Clone 118-18) is for Research Use Only.

 

EagleBio’s Mouse Monoclonal Antibody To S-Adenosylmethionine (Clone 118-18) was recently used in a study by the Department of Molecular and Cellular Oncology at the University of Texas MD Anderson Cancer Center in Houston, Texas.  This antibody has the following reactivities with related compounds: S-Adenosylmethionine: 100%, S-Adenosylhomocysteine: <1%, Adenosine: <1%, L-Methionine: <1%.

 

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

Posttranslational modifications to the intracellular domain of the EGFR are known to regulate EGFR functions; however, modifications to the extracellular domain and their effects remain relatively unexplored. Here, we determined that methylation at R198 and R200 of the EGFR extracellular domain by protein arginine methyltransferase 1 (PRMT1) enhances binding to EGF and subsequent receptor dimerization and signaling activation. Read More

 

(Source: https://www.jci.org/articles/view/82826)

Related Products:

Mouse Monoclonal Antibody To S-Adenosylmethionine (Clone 118-18)

Mouse Monoclonal Antibody to S-Adenosylmethionine (clone 84-3)

EagleBio Antibodies and Antigens

S-Adenosyl-L-Methionine (SAM) ELISA Assay Kit


Tatoos May Boost Immune System

image credit: https://www.prettydesigns.com

USCALOOSA, Ala. — There’s no known cure for the common cold, but receiving multiple tattoos can strengthen your immunological responses, potentially making you heartier in fighting off common infections, according to research by a trio of University of Alabama scholars. Read More

(Source: https://uanews.ua.edu/2016/03/want-to-avoid-a-cold-try-a-tattoo-or-twenty-says-ua-researcher/)

New Enhancements to
EagleBio’s SDMA Assay that is for the quantitative determination of SDMA
(Symmetric Dimethylarginine) in serum or plasma.

Nashua, NH March 7, 2016: Eagle Biosciences today announced the launch
of a new generation SDMA
(Symmetric Dimethylarginine) ELISA . This assay was developed and is manufactured
by DLD Diagnostika GmbH (www.DLD-Diagnostika.de)
in Germany. DLD is a worldwide leader in niche tests for autoimmune and
cardiovascular diseases as well as renal dysfunction.

“The enhancements that have been made to the SDMA
ELISA will be truly beneficial to our customers. It now offers a shorter incubation time,
smaller sample volume, and can be used with additional species such as canine
and feline. The new SDMA
Fast ELISA is now very fast and precise, delivering results in less
than 3 hours.“ said Dan Keefe, President of Eagle Biosciences.

This SDMA ELISA from Eagle Biosciences is currently for research
use only. Check out the links below,
visit the Eagle website, www.EagleBio.com,
or call 866-411-8023 for full details.

Related Products:

Oxidative
Stress Assay Kits

Cardiovascular
Assay Kits

ADMA
ELISA Assay KitADMA
(Asymmetric Dimethylarginine) / Arginine ELISA Assay KItADMA Ultrasensitive
ELISA Assay KitHomoarginine ELISA
Assay Kit Cardiovascular
Assay Kits

Related News:

Product
Highlights: SDMA (Symmetric Dimethylarginine) ELISA

Product
Highlights: SDMA (Symmetric Dimethylarginine) ELISA

September
2015: Eagle Biosciences Introduces New Fast ADMA ELISA Assay

EagleBio
Biomarker Spotlight: ADMA

New
Listing of ADMA Assay Publications

August
4, 2011: Eagle Biosciences Introduces ADMA ELISA Product Line

EagleBio’s Dopamine ELISA is for Research Use Only.

A recent study was conducted by Drexel University College of Medicine utilizing EagleBio’s Dopamine ELISA. Our Dopamine ELISA is designed for quantitative and very sensitive determination of dopamine in biological samples including serum, plasma, tissue, and cell culture samples. This assay provides a comprehensive array of sensitive tools to measure catecholamines and numerous neuroscience-related analytes on various types of samples. Check the product pages for full details on the kit or view the links below to find a new publication referencing our Dopamine ELISA .


New Publication:

Dopamine is produced in the rat spinal cord and regulates micturition reflex after spinal cord injury

Dopamine (DA) neurons in the mammalian central nervous system are thought to be restricted to the brain. DA-mediated regulation of urinary activity is considered to occur through an interaction between midbrain DA neurons and the pontine micturition center. Read More

.

(Source:  https://www.sciencedirect.com/science/article/pii/S001448861530128X)


IMAGE

IMAGE: A STUDY BY LJI RESEARCHERS IDENTIFIED A T CELL POPULATION THAT RENDERS NORMAL FOOD NON-ALLERGENIC. PHOTO CREDIT: LA JOLLA INSTITUTE FOR ALLERGY AND IMMUNOLOGY


LA JOLLA, CA–An estimated 15 million Americans suffer from food allergies, many of them children. These are non-trivial concerns, as food allergy or intolerance can cause symptoms ranging from a harmless skin rash to a potentially lethal anaphylactic shock. The good news is that many affected children outgrow their allergy, presumably as the immune system learns to tolerate food initially mistaken as “foreign”. Read more


(Source: https://www.eurekalert.org/pub_releases/2016-01/ljif-nsi012516.php)



Major progress has been made in recent years to produce functional insulin+ cells for cell replacement therapies to treat diabetes. These regenerative technologies include directed differentiation of embryonic stem cells and direct conversion from non-β cells such as liver cells, acinar cells, and others (Hebrok, 2012,Johannesson et al., 2015, Nostro and Keller, 2012, Schiesser and Wells, 2014,Zhou and Melton, 2008). Read more 

(Source: https://www.cell.com/cell-stem-cell/fulltext/S1934-5909(16)00004-7)


Trisha Wise-Draper, MD, PhD. (credit: Joe Fuqua, University of Cincinnati)


Researchers at the University of Cincinnati (UC) have discovered that a human cancer-causing gene, called DEK, can be detected in the plasma of head and neck cancer patients. DEK may help doctors understand how a person’s immune system could be used to treat cancer or predict outcomes for patients.


(Source:  https://www.eurekalert.org/pub_releases/2016-02/uoca-cgf021516.php)