Vitamin B6 Whole Blood HPLC Assay
The Vitamin B6 Whole Blood HPLC Assay is For Research Use Only
Size: 100 tests
Sensitivity: 2.5 U/mL
Dynamic Range: 10 – 270 U/mL
Incubation Time: 30 minutes
Sample Type: EDTA Whole Blood
Sample Size: 100 µL
Reference Values (Normal):
EDTA blood: 8.6 – 27.2 ng/ml
G.J. den Ottolander, Diagnostisch Kompas1997, S.441
It is suggested that each laboratory establish its own normal ranges
The vitamins pyridoxin, pyridoxal and pyridoxamin and the appropriate phosphate products are summarized as vitamin B6. All forms can be transformed into the active form pyridoxal-5- phosphate. Vitamin B6 functions as a coenzyme and is essential for more than 50 reactions in the protein, carbohydrate and fatty acid metabolism thereby synthesizing, transforming or degrading amino acids. In protein metabolism vitamin B6 supports the resorption of amino acids and their transport into the cells. Furthermore vitamin B6 contributes to the synthesis of neurotransmitters and amine products (histamine).
Due to the fact that vitamin B6 contributes to a variety of different reactions lack of vitamin B6 results in various clinical pictures as muscle dystrophia, skin diseases, or disturbances of the nervous system. High risk groups for reduced vitamin B6 concentrations in serum are lactating women, women taking oral contraceptives with high amount of estrogen and chronic drinkers. The Eagle Biosciences Vitamin B6 HPLC Assay makes it possible to determine the vitamin in an easy, fast and precise method. The kit includes all reagents in ready to use form for preparation and separation of the samples with exception of the columns (IC2100rp) and the controls (IC2101ko). Both can be supplied by Eagle Biosciences. Beside the complete test kits it is possible to order all components separately. Please request our single component price list.