Ocrelizumab (OCREVUS) ELISA Assay Kit

$1,380.00

The Ocrelizumab (OCREVUS) ELISA Assay Kit is intended for the estimation of Ocrelizumab in human serum and plasma. The Ocrelizumab ELISA Assay Kit is for research use only and not to be used for diagnostic procedures.

Ocrelizumab (OCREVUS) ELISA Assay Kit

The Ocrelizumab (OCREVUS) ELISA Assay Kit is For Research Use Only

Size: 1 x 96 wells
Calibrator Range: 7.8 – 500 ug/mL
Sensitivity: 6.5 ug/mL
Sample Size: 100 uL
Sample Type: Serum, Plasma
Incubation Time: 2 hours 30 minutes


Assay Background

Ocrelizumab, sold under the brand name Ocrevus, is a medication used for the treatment of multiple sclerosis (MS).It is a humanized anti-CD20 monoclonal antibody. It targets CD20 marker on B lymphocytes and hence is an immunosuppressive drug. Ocrelizumab binds to an epitope that overlaps with the epitope to which rituximab binds.

Assay Principle

The method employs the quantitative sandwich enzyme immunoassay technique. Human CD20 protein is precoated onto microwells. Samples and standards are pipetted into microwells and human Ocrelizumab present in the sample are bound. Then, Anti-Human IgG HRP conjugate is pipetted and incubated. After washing microwells in order to remove any non-specific binding, the ready to use substrate solution (TMB) is added to microwells and color develops proportionally to the amount of Ocrelizumab in the sample. Color development is then stopped by addition of stop solution. Absorbance is measured at 450 nm.


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Documents

Product Manual


Please note: All documents above are for reference use only and should not be used in place of the documents included with this physical product. If digital copies are needed, please contact us.