Neuropeptide Y ELISA Assay
The Neuropeptide Y ELISA Assay is For Research Use Only
Size: 1×96 wells
Sensitivity: 0.09 ng/ml
Dynamic Range: 0.01-100 ng/ml
Incubation Time: 4 hours
Sample Type: Blood collection, Plasma extraction, Tissue extraction, and CSF extraction
Sample Size: 50 µL
Alternative Names: Human Neuropeptide Y, NPY
SAMPLE COLLECTION & STORAGE INFORMATION
The sample collection and storage conditions listed below are intended as general guidelines.
Plasma – Collect blood samples into tubes containing EDTA. Gently rock the tubes several times immediately to prevent coagulation. Transfer the blood from tubes to centrifuge tubes containing aprotinin (0.6 TIU/ml blood) and gently rock for a few times to inhibit activity of proteinases. Plasma kept at – 80°C is stable for 1 month.
NPY gene encodes a neuropeptide that is widely expressed in the central nervous system and influences many physiological processes, including cortical excitability, stress response, food intake, circadian rhythms, and cardiovascular function. The neuropeptide functions through G protein-coupled receptors to inhibit adenylyl cyclase, activate mitogen-activated protein kinase (MAPK), regulate intracellular calcium levels, and activate potassium channels. A polymorphism in this gene resulting in a change of leucine 7 to proline in the signal peptide is associated with elevated cholesterol levels, higher alcohol consumption, and may be a risk factor for various metabolic and cardiovascular diseases. The protein also exhibits antimicrobial activity against bacteria and fungi.