Mouse SNCA Preformed Fibrils (Type 1)


The Eagle Biosciences Active Mouse Recombinant SNCA Preformed Fibrils (Type 1) is available in 100ug, 2 x 100ug, 5 x 100ug sizes. For Research Use Only. Contact us for bulk pricing.

SKU: SPR-324B Categories: ,

Mouse SNCA Preformed Fibrils (Type 1)

The Mouse SNCA Preformed Fibrils (Type 1) is For Research Use Only

Specificity: ~14.46 kDa
Species: Mouse
Expression System: E. coli
Buffer: PBS
Storage Temperature: -80ºC
Alternative Names: Active Mouse Recombinant Alpha Synuclein Preformed Fibrils (Type 1), Alpha synuclein PFFs, Alpha synuclein aggregates, Alpha synuclein protein aggregates, Active Alpha synuclein aggregates, Alpha-synuclein protein, Non-A beta component of AD amyloid protein, Non-A4 component of amyloid precursor protein, NACP protein, SNCA protein, NACP protein, PARK1 protein, Alpha synuclein monomers, SYN protein, Parkison disease familial 1 Protein

Product manufactured in Canada by StressMarq.

Assay Background

Alpha-Synuclein (SNCA) is expressed predominantly in the brain, where it is concentrated in presynaptic nerve terminals. Alpha-synuclein is highly expressed in the mitochondria of the olfactory bulb, hippocampus, striatum and thalamus. Functionally, it has been shown to significantly interact with tubulin, and may serve as a potential microtubule-associated protein. It has also been found to be essential for normal development of the cognitive functions; inactivation may lead to impaired spatial learning and working memory. SNCA fibrillar aggregates represent the major non A-beta component of Alzheimers disease amyloid plaque, and a major component of Lewy body inclusions, and Parkinson’s disease. Parkinson’s disease (PD) is a common neurodegenerative disorder characterized by the progressive accumulation in selected neurons of protein inclusions containing alpha-synuclein and ubiquitin.

Related Products

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Alpha Synuclein Preformed Fibrils (Type 1)
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Additional Information

Comparative Protein Graph

Mouse SNCA Preformed Fibrils (Type 1)

Package Inserts

Please note: All documents above are for reference use only and should not be used in place of the documents included with this physical product. If digital copies are needed, please contact us.

Product Citations