MMP-7 ELISA Assay Kit
The MMP-7 ELISA Assay Kit is For Research Use Only
Product Developed and Manufactured in the USA
Size: 1×96 wells
Sensitivity: 1.0 ng/mL
Dynamic Range: 4 – 64 ng/mL
Incubation Time: 2.25 hours
Sample Type: Serum
Sample Size: 50 µL
Alternative Names: Matrix Metalloproteinase 7
STORAGE AND STABILITY
1. Store the MMP-7 calibrators and standards are stable for up to 3 months at 2-8°C.
2. Keep microplate sealed in a dry bag with desiccants, store at 2-8°C.
3. Do not expose reagents to heat, sun, or strong light.
MMP-7 proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP’s are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. The MMP-7 enzyme degrades proteoglycans, fibronectin, elastin and casein and differs from most MMP family members in that it lacks a conserved C-terminal protein domain. The enzyme is involved in wound healing, and studies in mice suggest that it regulates the activity of defensins in intestinal mucosa. The gene is part of a cluster of MMP genes which localize to chromosome 11q22.3.