Human Insulin Biotinylated

Additional Information

Why has insulin a continuously emerging field of research?

Diabetes truly begins and ends on a microscopic level in the pancreas within a cluster of islets containing beta cells called the Islets of Langerhans. This is where millions of islet cells coordinate intermittent secretory bursts of insulin into the portal veins. Beta cells normally release insulin so that the glucose can be efficiently metabolized in normal, healthy people. However, in diabetic individuals, beta cells fail, resulting in their inability to appropriately respond to increases in glucose in the blood. Glucose is the principal stimulus for insulin secretion, though other macronutrients (ie. Carbohydrates, proteins, fats), hormones, humoral factors and neural input may modify this response.^1,2
Insulin and insulin resistance has been at the forefront of medical research with obesity and diabetes reaching epidemic levels across the world. There are various fields of research that surround measuring, analyzing, and understanding this biomarker and its role across a wide range of physiological processes. The influences on its synthesis and secretion, in addition to its actions from the cellular level to the whole body level, has significant implications for much chronic disease.¹ It is only in scientific laboratories that insulin’s complex actions at the cellular level can be observed. ¹

Why would you want to use Recombinant Biotinylated Human Insulin?

As described above, insulin has quite an intricate role in the body and a significant impact on various organs, tissues, and metabolic functions which makes uniform testing impossible for researchers. Laboratories worldwide have dedicated their time and resources to various aspects of diabetes and obesity research ranging from general insulin and insulin resistance studies to islet cell replacement studies. Our Recombinant Biotinylated Human Insulin is a stable, multi-method tool for every diabetes and obesity research need.