Human [Arg3] IGF-I (Receptor Grade)


The Eagle Bioscience’s Human [Arg3] IGF-I (Receptor Grade) is for research use only and not to be used for diagnostic procedures.

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Human [Arg3] IGF-I (Receptor Grade)

The Eagle Bioscience’s Human [Arg3] IGF-I (Receptor Grade) is for research use only and not to be used for diagnostic procedures.

Product Specifications


IGF-I is produced in E.coli using a patented expression system and the IGF-I is correctly folded and purified by several chromatography steps to yield Receptor Grade IGF-I.


Human [Arg3] insulin-like Growth Factor-I is a 70 amino acid analogue of IGF-I comprising the complete human IGF-I sequence with the substitution of an Arginine for the Glutamine at position 3. Human [Arg3] IGF-I is more potent than IGF-I in vitro and in vivo. This increased potency is due to reduced binding of human [Arg3] IGF-I to most of the IGF binding proteins which modify the biological actions of IGF-I. This item binds to the type 1 IGF receptor with a similar affinity to wild-type IGF-I. This is a high-quality research reagent for use in studies on cell growth, IGF receptors, and IGF binding proteins. 

  • Purity: >95 % (as determined by HPLC analysis)
  • Quantity: 1 mg
  • Molecular Weight: 7676 daltons – confirmed by Mass Spectrometry
  • N-terminal sequence analysis of recombinant product: 5 residues >95% single sequence
  • Biological Activity: Stimulation of protein synthesis in rat L6 myoblasts (ED50 < 10 ng/ml) IGF type 1 receptor binding assay (ED50 < 10 ng/ml) IGF binding protein assay: ED50 > 50 ng/ml)
  • Endotoxin (LAL): <0.1 EU/ug
  • Storage/Stability: At least 2 years at 2-4°C (lyophilized)
  • Appearance: White Powder
  • State: Dried from 0.1 M acetic acid under dry nitrogen at a slight vacuum (-25kPa)

Related Products

Receptor Grade IGF-I Recombinant Protein
Human Arg3 IGF-1 Biotin
Rodent IGF-I ELISA Assay

Package Inserts

Please note: All documents above are for reference use only and should not be used in place of the documents included with this physical product. If digital copies are needed, please contact us.

Product Citations