Anti-tTG sIgA/IgA ELISA Assay Kit
The Anti-tTG sIgA/IgA ELISA Assay Kit is For Research Use Only
Size: 12 x 8 wells
Sensitivity: 2.1 mU/g
Incubation Time: 2 hours 15 minutes
Sample Type: Stool
Sample Size: 50 µl
Controls Included
Product Developed and Manufactured in Germany by Immuchrom
Product Support in the United States
Assay Background
Celiac disease is a chronic illness of the small intestinal mucous membrane. The reason is an intolerance against gluten, which is found in many cereals. This food intolerance against cereal proteins leads to a production of auto-antibodies against tissue transglutaminase, which is the major antigen for endomysium antibodies.
The intake of gluten-containing food leads to an inflammation of the small intestinal mucous membrane, which results in a reduced absorption of nutrients. The symptoms of the disease are reduction of weight, diarrhea, vomitus, anorexia and tiredness. The growth of children is impaired. The characteristic of the symptoms might be different. The only therapeutic treatment is a gluten-free diet. A non-treated celiac disease increases the risk of non-Hodgkin-lymphoma and colon cancer. Celiac disease is associated with type 1 diabetes mellitus in five to ten percent of the patients. Women are more often affected than men. The outcome of the disease is pronounced during infancy and in ages between 30 and 40 years old.
Applications:
- Food Intolerance
- Monitoring of an elimination diet
The Eagle Biosciences Anti-human tissue transglutaminase sIgA / IgA kit allows an easy, rapid and precise quantitative determination of the antibodies in biological samples. The kit includes all reagents ready to use for preparation of the samples.
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