The Human Recombinant RNase 7 Protein
The Human Recombinant RNase 7 Protein is For Research Use Only
Synonyms: Ribonuclease 7, RNase7, Skin-derived antimicrobial protein 2
Uniprot ID: Q9H1E1
Source: Human
Expression Host: CHO-based cell line (expressed by QMCF Technology)
Buffer: 10 mM Na-acetate, pH 5.0; 150 mM NaCl
Molecular Weight:
Approximately 14.5 kDa, a single non-glycosylated polypeptide chain containing 128 amino acids.
Purification:
Purified by affinity chromatography and gel-filtration from serum-free CHO growth media.
Concentration:
0.23 mg/ml Concentration of the protein is determined by NanoDrop using calculated Mw and extinction coefficient equation.
Endotoxine level: Not determined
Biological properties: Not determined
Shipping:
Shipped in dry-ice
Storage:
Store at -70°C upon receipt. Recommended to aliquot into smaller quantities.
Background: RNase7 exhibits a potent RNase activity. Recombinant RNase 7 exhibited antimicrobial activity against uropathogens at low micromolar concentrations by disrupting the microbial membrane (Spencer et al. 2013). Has broadspectrum antimicrobial activity against many pathogenic microorganisms and remarkably potent activity against a vancomycin resistant Enterococcus faecium.
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