Human CDNF Mouse Monoclonal Antibody
The Human CDNF Mouse Monoclonal Antibody is For Research Use Only
Immunogen: Human CDNF
Uniprot ID: Q49AH0
Alternative Names: ARMETL1
Clone: 7D6
Clonality: Mouse monoclonal
Class: IgG1
Reactivity: Human, mouse; others not tested
Application: ELISA, WB, IF
Purification: purified by protein G affinity chromatography
Buffer: PBS pH 7.4, with 0.1% sodium azide
Concentration: 1 mg/ml
Unit Size: 100 µg
Related Products: Mono- and polyclonal antibodies to human CDNF
Shipping: This product is shipped in non-frozen liquid form in ambient conditions
Storage: Store at – 20 or -70 °C upon receipt. Divide antibody into aliquots prior usage. Avoid multiple freeze-thaw cycles as product degradation may result.
Alternative Names: Cerebral Dopamine Neurotrophic Factor
Protocol: ELISA – 1:5000 to 1:10 000; WB – 1:1000 to 1:4000; IF – 1:100 to 1:3000; Monoclonal antibody working dilution has to be established practically for each particular antigen and assay format
Background: CDNF is a trophic factor for midbrain dopamine neurons in vivo. It prevents the 6-OHDA- (Lindholm et al. 20007; Voutilainen et al., 2011) and MPTP-induced degeneration (Airavaara et al., 2012) of dopamine neurons in rodent models of Parkinson’s disease. When administered after 6-OHDA or MPTP –lesioning it restores the dopaminergic function and prevents degeneration of dopamine neurons in substantia nigra pars compacta
Product Developed and Manufactured in Germany by Icosagen
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