Eagle Bioscience’s Total Testosterone ELISA Assay Kit was used in a recent study. This kit is part of our line of Steroid Assay Kits which is a line of highly sensitive and specific assays used to detect a variety of samples in serum, plasma, tissue, urine, and saliva.

Impact of resistance training on body composition and metabolic syndrome variables during androgen deprivation therapy for prostate cancer: a pilot randomized controlled trial

Background

Prostate cancer patients on androgen deprivation therapy (ADT) experience adverse effects such as lean mass loss, known as sarcopenia, fat gain, and changes in cardiometabolic factors that increase risk of metabolic syndrome (MetS). Resistance training can increase lean mass, reduce body fat, and improve physical function and quality of life, but no exercise interventions in prostate cancer patients on ADT have concomitantly improved body composition and MetS. This pilot trial investigated 12 weeks of resistance training on body composition and MetS changes in prostate cancer patients on ADT. An exploratory aim examined if a combined approach of training and protein supplementation would elicit greater changes in body composition.

Conclusions

A 12-week resistance training intervention effectively improved sarcopenia, body fat %, strength and quality of life in hypogonadal prostate cancer patients, but did not change MetS or physical function. PRO did not offer additional benefit in improving body composition.

Dawson, Jacqueline K., et al. “Impact of Resistance Training on Body Composition and Metabolic Syndrome Variables during Androgen Deprivation Therapy for Prostate Cancer: a Pilot Randomized Controlled Trial.” BMC Cancer, vol. 18, no. 1, 3 Apr. 2018, p. 368., doi:10.1186/s12885-018-4306-9.

Testosterone: Why Higher Levels are Connected to Prostrate Enlargement

 

A recent study at the University of California – Santa Barbara (UCSB) focused on testosterone levels in a cohort of men in the US and compared results to previous research on a group of 350 adult males in Tsimane,Bolivia where researchers examined the prevalence of Benign prostatic hyperplasia (BPH)(aka. prostrate enlargement). BPH is one of the most prevalent diseases among aging men in the US.  The causes and underlying factors that contribute to this disease have not yet been identified, thus the reason for this study.

It has been explained in recent publicationsthat men in Tsimane have 30% lower testosterone levels because of environmental (numerous parasites and pathogens) and lifestyle factors (hunting, fishing,foraging: causing the need to maintain testosterone in order to maintain muscle mass). Antropologists from UCSB believe that increased levels of testosterone compromises the immune system in order to keep it low in environments where parasites and pathogens are rampant. It was discovered that the cases of advanced prostrate enlargement were nonexistent.

Because men in the US have a higher level of testosterone and their levels decrease with age, there has been a trend to supplement this decline with replacement therapy. It is believed that interfering with Mother Nature may not be the best choice and we are left to wonder, is this what is causing the increase in prostrate cancer and other diseases?  Read More

image above from:https://www.ia.ucsb.edu/

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