Tag: EagleBio

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University of Calgary Study: EagleBio’s ​Ultra-Sensitive Streptavidin Coated 96 Well Microplate

by Eagle Biosciences

-Ultra-sensitive-streptavidin-coated-plate

Ultra-Sensitive Streptavidin Coated 96 Well Microplate is for Research Use Only.

EagleBio’s Ultra-Sensitive Streptavidin Coated 96 Well Microplate was recently used in a study by the University Calgary. See publication below:

Identification of protein-protein interactions between the TatB and TatC subunits of the twin-arginine translocase system and respiratory enzyme specific chaperones.

The Twin-arginine translocation (Tat) pathway serves for translocation of fully folded proteins across the cytoplasmic membrane in bacterial and chloroplast thylakoid membranes. The Escherichia coli Tat system consists of three core components: TatA, TatB, and TatC. The TatB and TatC subunits form the receptor complex for Tat dependent proteins. Read More

(Source: https://www.ncbi.nlm.nih.gov/pubmed/26826271)

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Managing Microglia and Treating Neurodegenerative Disease

by Eagle Biosciences


The area of a brain lacking Mer and Axl that Salk scientists call the ‘trail of death

Image credit: Salk Institute


Even when the body has reached the peak of development, there are certain regions of the brain where neurons continue to grow. In order to keep these areas neat and clean, the brain recruits immune cells uniquely designed to clear out the dead and dying cells in the brain. Read More

(Source: https://www.labroots.com/trending/immunology/2833/managing-microglia-treating-neurodegenerative-disease)

Further reading

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EagleBio’s Updated SDMA Assay- Faster results, Multiple species, Smaller Sample Size

by Eagle Biosciences

EagleBio's New SDMA Assay

 

SDMA (Symmetric Dimethylarginine) ELISA is for Research Use Only.

SDMA (Symmetric Dimethylarginine) ELISA is one of the unique assays in the this Oxidative Stress Assay Kit Line that offers a variety of advantages over competing kits such as excellent specificity, sensitivity, and excellent correlation to LC-MS/MS.  

EagleBio’s SDMA (Symmetric Dimethylarginine) ELISA NOW has some new enhancements to offer more benefits and further assist our customers in their kidney function research.

Assay Updates:

  • Updated Assay protocol
  • Results in 3 hours rather than overnight
  • Human, Canine, and Feline SDMA can be measured
  • Small Sample size required – just 20 µl
  • Strong Correlation with LC/MS

The new  SDMA Fast ELISA is now very fast and precise. This test delivers for the first time precise results in less than 3 hours!  Check out the product page for more details Here.

Related Products:

Oxidative Stress Assay Kits

Cardiovascular Assay Kits

ADMA ELISA Assay KitADMA (Asymmetric Dimethylarginine) / Arginine ELISA Assay KItADMA Ultrasensitive ELISA Assay KitHomoarginine ELISA Assay Kit Cardiovascular Assay Kits

 

Related News:

Product Highlights: SDMA (Symmetric Dimethylarginine) ELISA

September 2015: Eagle Biosciences Introduces New Fast ADMA ELISA Assay

EagleBio Biomarker Spotlight: ADMA

New Listing of ADMA Assay Publications

August 4, 2011: Eagle Biosciences Introduces ADMA ELISA Product Line

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Controlling Cell Turnover in the Intestinal Lining

by Eagle Biosciences

Frey_sheddingCells, web.jpg

Image credit: www.chla.org

The lining of the intestine is the most rapidly-renewing tissue in the body. Routine shedding of epithelial cells from this lining is a key element of tissue turnover, and is thus essential to maintaining optimal health. Altered shedding is associated with multiple disorders, ranging from inflammatory bowel disease (IBD) to colorectal cancer. Read More

(Source: https://www.chla.org/press-release/controlling-cell-turnover-the-intestinal-lining)

 

Related Kits:

Gastrointestinal Kits

Human EGF ELISA Kit

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Gas in the gut isn’t just an embarrassment – it might be an important indication of your body’s health.

by Eagle Biosciences

I hate to say it, but doctors have something of a flatulence problem: at the moment, they know embarrassingly little about the bubbles brewing in your bowels.

“What comes out of the backside only tells us about the last 20cm of the gut,” says Peter Gibson at Monash University in Victoria, Australia. Gibson wants to know what’s happening in the previous 130cm of the digestive tract, leading up to that final explosion. Read More

(Source: https://www.bbc.com/future/story/20160331-why-we-need-a-better-way-to-measure-farts)

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Moorfields Acuity Chart: Novel Sight Test Detects Early Age-Related Macular Degeneration

by Eagle Biosciences

Left: conventional chart. Right: Moorfields Acuity Chart. Image credit: Nilpa Shah et al.

 Image above from: www.sci-news.com 


An international team of scientists, led by Prof. Roger Anderson from the University of Ulster at Coleraine and the NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, has designed a test that can spot the first stages of sight loss in age-related macular degeneration. Read More

(Source: https://www.sci-news.com/medicine/moorfields-acuity-chart-early-age-related-macular-degeneration-03740.html)

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Stem Cells Regenerate Human Lens After Cataract Surgery, Restoring Vision

by Eagle Biosciences


               The clouded lens of a cataract in human eye. Photo courtesy of Wikimedia

Approach may have broad therapeutic implications on tissue and organ repair

Researchers at University of California, San Diego School of Medicine and Shiley Eye Institute, with colleagues in China, have developed a new, regenerative medicine approach to remove congenital cataracts in infants, permitting remaining stem cells to regrow functional lenses. Read more


(Source: https://ucsdnews.ucsd.edu/)

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Texas Study: EagleBio’s Mouse Monoclonal Antibody to S-Adenosylmethionine (Clone 118-18)

by Eagle Biosciences

 

Anibody

 

Mouse Monoclonal Antibody to S-Adenosylmethionine (Clone 118-18) is for Research Use Only.

 

EagleBio’s Mouse Monoclonal Antibody To S-Adenosylmethionine (Clone 118-18) was recently used in a study by the Department of Molecular and Cellular Oncology at the University of Texas MD Anderson Cancer Center in Houston, Texas.  This antibody has the following reactivities with related compounds: S-Adenosylmethionine: 100%, S-Adenosylhomocysteine: <1%, Adenosine: <1%, L-Methionine: <1%.

 

PRMT1-mediated methylation of the EGF receptor regulates signaling and cetuximab response

Posttranslational modifications to the intracellular domain of the EGFR are known to regulate EGFR functions; however, modifications to the extracellular domain and their effects remain relatively unexplored. Here, we determined that methylation at R198 and R200 of the EGFR extracellular domain by protein arginine methyltransferase 1 (PRMT1) enhances binding to EGF and subsequent receptor dimerization and signaling activation. Read More

 

(Source: https://www.jci.org/articles/view/82826)

Related Products:

Mouse Monoclonal Antibody To S-Adenosylmethionine (Clone 118-18)

Mouse Monoclonal Antibody to S-Adenosylmethionine (clone 84-3)

EagleBio Antibodies and Antigens

S-Adenosyl-L-Methionine (SAM) ELISA Assay Kit