Trastuzumab mAb-based ELISA Assay
The Trastuzumab mAb-based ELISA Assay is For Research Use Only
Size: 1×96 wells
Sensitivity: 2 ng/mL
Dynamic Range: 6 – 200 ng/mL
Incubation Time: 2 hours
Sample Type: Serum, Plasma
Sample Size: 10 µL
Alternative Names: Herceptin, Herclon
The drug Trastuzumab (trade names Herceptin® or Herclon®) is a recombinant DNA-derived humanized monoclonal antibody that selectively targets the extracellular domain of the human epidermal growth factor receptor 2 protein (HER2). The antibody is an IgG1 kappa that contains human framework regions with the complementarity-determining regions of a murine anti-p185 HER2 antibody that binds to HER2. Trastuzumab blood concentrations throughout the dosing interval expected to be remaining above those considered necessary for anticancer activity. Furthermore, in a separate analysis, patients with the lowest Trastuzumab serum trough concentrations had the highest rate of disease progression and shortest overall survival. This Eagle Biosciences ImmunoGuide Trastuzumab ELISA (mAb-based) is developed for the specific measurement of Trastuzumab in serum, plasma,and other biological fluids by the advantage of using a site-directed VME-5A6b mouse monoclonal antibody (mAb) specific for Trastuzumab only.
STORAGE AND STABILITY
The kit is shipped at ambient temperature and should be stored at 2-8°C. Keep away from heat or direct sun light. The microtiter strips are stable up to the expiry date of the kit in the broken, but tightly closed bag when stored at 2–8°C.