Mouse IL-12 p70 ELISA Assay Kit
For Research Use Only
Size: 1×96 wells
Sensitivity: 7 pg/mL
Dynamic Range: 31.25 – 2000 pg/ml
Incubation Time: 3.5 hours
Sample Type: Serum, Plasma, Cell Culture
Sample Size: 100 µl
$390.00
The Eagle Biosciences Mouse Interleukin 12 p70 (IL-12 p70) ELISA Assay Kit (enzyme-linked immunoassay kit) is intended for the quantitative determination of mouse Interleukin 12 p70 (IL-12 p70) concentrations in cell culture supernates, serum, and plasma. The Eagle Biosciences Mouse Interleukin 12 p70 (IL-12 p70) ELISA Assay Kit is for research use only and not to be used in diagnostic procedures.
For Research Use Only
Size: 1×96 wells
Sensitivity: 7 pg/mL
Dynamic Range: 31.25 – 2000 pg/ml
Incubation Time: 3.5 hours
Sample Type: Serum, Plasma, Cell Culture
Sample Size: 100 µl
IL-12 p70 has been shown to have multiple effects on T lymphocytes and natural killer (NK) cells. Some of these effects include the induction of IFN-γ and TNF production by T and NK cells, the enhancement of cytotoxic activity of T and NK cells and the stimulation of T and NK cell proliferation. IL-12 p70 has also been shown to be a central mediator of the cell-mediated immune response by promoting Th1 development (7-11). Cell surface staining for IL-12 p70 on a human monocytic and a mouse macrophage cell line has been reported, suggesting that membrane-associated IL-12 p70 may exist (12). Cells known to produce IL-12 p70 include macrophages, dendritic cells, monocytes, Langerhans cells, neutrophils, and keratinocytes. Although a human B cell line has been shown to produce IL-12 p70(2), fresh B cells are apparently not producers of IL-12 p70.