MASP-2 ELISA Assay Kit


The MASP-2 ELISA Assay Kit is to be used for the in vitro quantitative determination of
human MASP-2 in serum, plasma and cell culture supernatant samples. This kit is intended
for laboratory research use only and is not for use in diagnostic or therapeutic procedures. The MASP-2 ELISA is Patent protected by patent 09/874,238 and PCT/DK2004/000338. License rights on the Patents are acquired from Natimmune S/A, Denmark.

MASP-2 ELISA Assay Kit

The MASP-2 ELISA Assay Kit is For Research Use Only

Sizes: 1 x 96 wells
Sensitivity: 1.6 ng/mL
Dynamic Range: 1.6 – 100 ng/mL
Sample Size: 100 uL
Incubation Time: 3 hours 30 minutes
Sample Type: Serum, Plasma, Cell Culture Supernatant

Controls Not Included

Assay Background

MASP-2 is a MBL associated serine protease. Mannan-binding lectin (MBL) and ficolins, in
complex with MASPs, are capable of activating the complement system, thus mediating the destruction of infectious agents. After oligomerisation of MBL (or L-Ficolin) MASP-2 will be bound and activated. Activated MASP-2 cleaves C4 and C2 and is crucial for the activation of downstream complement components. MASP-2 deficiency will result in an increased susceptibility for infections (e.g. leukemia patients in chemotherapy are at high risk of serious infections). Even more so than MBL deficiency, because MASP-2 is also required for complement activation by H- and L-ficolin. The ELISA detects MASP-2 in serum and plasma. The MASP-2 levels in plasma from healthy individuals range from 170 to 1196 ng/ml.

Please notice there is no guarantee for any batch-to-batch variability for this specific kit. We advise to use the same lot number if multiple kits are needed for a larger project. For more information or larger quantities please contact us at

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Product Manual

Please note: All documents above are for reference use only and should not be used in place of the documents included with this physical product. If digital copies are needed, please contact us.

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