Homoarginine ELISA Assay Kit


The Homoarginine ELISA Assay Kit is intended to be used for the quantitative determination of homoarginine in serum, plasma, or cell culture samples. The Homoarginine ELISA Assay Kit is for reseach use only and not for use in diagnostic or therapeutic procedures.
This product was previously known as HOM39-K01.

SKU: EA205/96 Categories: , , Tags: , ,

Homoarginine ELISA Assay Kit

Homoarginine ELISA Assay kit was developed and manufactured in Germany by DLD Diagnostika 

Size: 1×96 wells
Sensitivity: 0.05 µmol/L
Dynamic Range: 0.03 – 7.0 µmol/l
Incubation Time: 2.5 hours
Sample Type: Serum, Plasma, Cell Culture
Sample Size: 20 µL
Controls Included
For Research Use Only

Assay Background

Homoarginine is a non-essential cationic amino acid, which is formed from lysine.  In vitro and in vivo, homoarginine shows characteristics similar to arginine. Epidemiological investigations in two large independent cohorts, namely the German diabetes dialysis (4D) study and the Ludwigshafen Risk and Cardiovascular Health (LURIC) study have identified homoarginine as useful predictor of cardiovascular events and mortality.

Beyond potential cardiovascular indications, homoarginine concentrations are known to be directly correlated with kidney function and are known to be significantly associated with the progression of chronic kidney disease (CKD). Low homoarginine concentrations may be an early indicator of kidney failure and may be a potential target for the prevention of disease progression which needs further investigation. Furthermore homoarginine could be a useful marker for the monitoring of hemodialysis patients.

Eagle Biosciences offers a competitive Homoarginine ELISA Assay using the microtiter plate format. The correlation of the ELISA method to LC-MS is exceptionally good. In addition, no interferences with any therapeutic drugs are observed. The Homoarginine ELISA Assay  method allows the measurement of large series of samples.

Related Products

ADMA (Asymmetric Dimethylarginine) / Arginine ELISA Assay Kit



Homoarginine ELISA Assay Kit in the News

EagleBio Biomarker Spotlight: Homoarginine

Eagle Biosciences Continues Product Line Expansion with launch of New Homoarginine ELISA kit

Additional Information

Assay Principle

The competitive Homoarginine ELISA Assay Kit uses the microtiter plate format. Homoarginine is bound to the solid phase of the microtiter plate. Homoarginine in the samples is acylated and competes with solid phase bound Homoarginine for a fixed number of rabbit anti-Homoarginine antiserum binding sites. When the system is in equilibrium, free antigen and free antigen-antiserum complexes are removed by washing. The antibody bound to the solid phase Homoarginine is detected by anti-rabbit/peroxidase. The substrate TMB / peroxidase reaction is monitored at 450 nm. The amount of antibody bound to the solid phase Homoarginine is inversely proportional to the Homoarginine concentration of the sample.

Typical Standard Curve

Homoarginine ELISA Assay Standard Curve

Package Inserts

Please note: All documents above are for reference use only and should not be used in place of the documents included with this physical product. If digital copies are needed, please contact us.

Product Citations