Homoarginine ELISA Assay Kit
Homoarginine ELISA Assay kit was developed and manufactured in Germany by DLD Diagnostika
Size: 1×96 wells
Sensitivity: 0.05 µmol/L
Dynamic Range: 0.03 – 7.0 µmol/l
Incubation Time: 2.5 hours
Sample Type: Serum, Plasma, Cell Culture
Sample Size: 20 µL
For Research Use Only
Homoarginine is a non-essential cationic amino acid, which is formed from lysine. In vitro and in vivo, homoarginine shows characteristics similar to arginine. Epidemiological investigations in two large independent cohorts, namely the German diabetes dialysis (4D) study and the Ludwigshafen Risk and Cardiovascular Health (LURIC) study have identified homoarginine as useful predictor of cardiovascular events and mortality.
Beyond potential cardiovascular indications, homoarginine concentrations are known to be directly correlated with kidney function and are known to be significantly associated with the progression of chronic kidney disease (CKD). Low homoarginine concentrations may be an early indicator of kidney failure and may be a potential target for the prevention of disease progression which needs further investigation. Furthermore homoarginine could be a useful marker for the monitoring of hemodialysis patients.
Eagle Biosciences offers a competitive Homoarginine ELISA Assay using the microtiter plate format. The correlation of the ELISA method to LC-MS is exceptionally good. In addition, no interferences with any therapeutic drugs are observed. The Homoarginine ELISA Assay method allows the measurement of large series of samples.