Eculizumab ELISA Assay Kit
The Eculizumab ELISA Assay Kit is For Research Use Only
Size: 12×8 wells
Sensitivity: < 0.2 µg/mL
Standard Range: 0.2-100 µg/ml
Incubation Time: 2.5 hours
Sample Type: Serum, Plasma, Cell Culture Supernatant
Sample Size: 100 µL
Alternative Name: Soliris
Assay Background for Eculizumab ELISA
Eculizumab, sold under the trade name Soliris, is a medication used to treat paroxysmal nocturnal hemoglobinuria (PNH) and atypical hemolytic uremic syndrome (aHUS). It is a humanized monoclonal antibody functioning as a terminal complement inhibitor. In people with PNH, it reduces both the destruction of red blood cells and need for blood transfusion, but does not appear to affect the risk of death. Eculizumab was the first drug approved for each of its uses, and its approval was granted on the basis of small clinical trials.
Sample Preparation and Storage:
Blood is taken by venipuncture. Serum is separated after clotting by centrifugation. Plasma can be used, too. Lipaemic, hemolytic or contaminated samples should not be run. Repeated freezing and thawing should be avoided. If samples are to be used for several assays, initially aliquot samples and keep at – 20°C. Samples can be stored at -20°C or -80⁰C. Avoid repeated freeze-thaw cycles.