Anti-CCP ELISA Assay Kit
Anti-CCP ELISA Assay Kit Developed and Manufactured by Medipan
Size: 1×96 wells
Sensitivity: 1.2 U/mL
Dynamic Range: 1 – 2000 U/mL
Incubation Time: 2 hours
Sample Type: Serum, Plasma
Sample Size: 5 µL
Alternative Names: Human Anti-CCP ELISA, Human CCP IgG ELISA
For Research Use Only
Negative: < 30 U/ml Positive: ≥ 30 U/ml It is recommended that each laboratory establishes its own normal and pathological reference ranges for serum anti-CCP antibodies levels as usually done for other diagnostic parameters, too. Therefore, the above mentioned reference values provide only a guide.
Rheumatoid Arthritis (RA) is most often diagnosed by the measurement of rheumatoid factors (RF). The rheumatoid factor is an antibody directed against the Fc-region of IgG. It appears mainly as IgM antibody but also as IgA or IgG subgroup. Rheumatoid factors are present in sera of 70 – 80 % of patients suffering from rheumatoid arthritis. But it is not specific for RA since it will also be found in healthy persons. The incidence depends on the age: for young people it is 1 – 4 %, for older persons it may reach up to 25 %.
The advantage of CCP antibodies is a higher sensitivity and specificity for the diagnosis of rheumatoid arthritis in comparison to the rheumatoid factors alone. Anti-CCP is often found at a very early state of the disease and it has a high predictive value for development of the disease.