Cardiovascular and Oxidative Stress Assay Kit

Anti-ACE II Antibodies ELISA

$2,080.00

The Anti-ACE II Antibodies ELISA is designed for the determination of IgG antibodies against ACE-II in human serum and plasma. This product is intended for research use only and not for use in diagnostic or clinical procedures.

SKU: 16000 Categories: , ,

Anti-ACE II Antibodies ELISA

The Anti-ACE II Antibodies ELISA is For Research Use Only

Size: 1×96 wells
Sensitivity: 1.25 U/ml
Dynamic Range: 1.25 U/ml and 40 U/ml
Incubation Time: 3 hours 20 minutes
Sample Type: Serum and plasma
Sample Size: 100 µL
Alternative Names: Angiotensin Converting Enzyme 2
Controls Included

Assay Principle

The Angiotensin-converting enzyme 2 (ACE-II)-EIA is an antibody screening test. ACE-II enzyme has been pre-coated onto a microtiter plate. During the first incubation the anti-ACE-II-antibodies of the samples are immobilized on the plate. The autoantibodies are detected with a HRP labeled antihuman IgG antibody. In the following enzymatic substrate reaction the intensity of the colour correlates with the concentration and/ or avidity of anti-ACE-II antibodies.

Additional Information

Assay Background

Angiotensin-Converting-Enzyme 2 (ACE-II) is a zinc containing metalloenzyme expressed on endothelial and other cells. ACE-II is an enzyme expressed by cells in the lungs, arteries, heart, kidney, and intestines. ACE-II lowers blood pressure by catalysing the hydrolysis of angiotensin II (Ang-II) into angiotensin (1–7). ACE-II counters the activity of the related angiotensin-converting enzyme by reducing Ang-II and increasing Ang(1-7).

Package Inserts

Please note: All documents above are for reference use only and should not be used in place of the documents included with this physical product. If digital copies are needed, please contact us.

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