Anti-ACE II Antibodies ELISA


The Anti-ACE II Antibodies ELISA is designed for the determination of IgG antibodies against ACE-II in human serum and plasma. This product is intended for research use only and not for use in diagnostic or clinical procedures.

Anti-ACE II Antibodies ELISA

The Anti-ACE II Antibodies ELISA is For Research Use Only

Size: 1×96 wells
Sensitivity: 1.25 U/ml
Dynamic Range: 1.25 U/ml and 40 U/ml
Incubation Time: 3 hours 20 minutes
Sample Type: Serum and plasma
Sample Size: 100 µL
Alternative Names: Angiotensin Converting Enzyme 2
Controls Included

Assay Principle

The Angiotensin-converting enzyme 2 (ACE-II)-EIA is an antibody screening test. ACE-II enzyme has been pre-coated onto a microtiter plate. During the first incubation the anti-ACE-II-antibodies of the samples are immobilized on the plate. The autoantibodies are detected with a HRP labeled antihuman IgG antibody. In the following enzymatic substrate reaction the intensity of the colour correlates with the concentration and/ or avidity of anti-ACE-II antibodies.

Related Products

Human ACE2 ELISA Assay

Additional Information

Assay Background

Angiotensin-Converting-Enzyme 2 (ACE-II) is a zinc containing metalloenzyme expressed on endothelial and other cells. ACE-II is an enzyme expressed by cells in the lungs, arteries, heart, kidney, and intestines. ACE-II lowers blood pressure by catalysing the hydrolysis of angiotensin II (Ang-II) into angiotensin (1–7). ACE-II counters the activity of the related angiotensin-converting enzyme by reducing Ang-II and increasing Ang(1-7).


Product Manual