Adenovirus Antigen ELISA Assay
Adenovirus Antigen ELISA Assay is developed and manufactured in the USA
Size: 1×96 wells
Sensitivity: Cut-Off Control
Incubation Time: 2 hours
Sample Type: Stool
Sample Size: 50mg
Alternative Names: Fecal Adenovirus Antigen ELISA
For Research Use Only
Acute diarrheal disease in young children is a major cause of morbidity worldwide and is a leading cause of mortality in developing countries. Research has shown that enteric adenoviruses, primarily Ad40 and Ad41, are a leading cause of diarrhea in many of these children, second only to the rotaviruses. However many different symptoms can manifest, depending on the type of infecting Adenovirus. There are 49 distinct serotypes that can cause infections in humans.
The diarrhea resulting from enteric adenoviruses is longer in duration than that caused by the rotaviruses, usually lasting 7 – 8 days. Adenovirus infections often show up as conjunctivitis, tonsillitis (which may look exactly like strep throat and cannot be distinguished from strep except by throat culture), an ear infection, or croup. Adenoviruses can also cause gastroenteritis (stomach flu). A combination of conjunctivitis and tonsillitis is particularly common with adenovirus infections. Small children are especially prone to develop adenovirus bronchiolitis or pneumonia, both of which can be severe. In babies, adenoviruses can also cause coughing fits that are almost exactly like whooping cough. Adenoviruses can also lead to viral meningitis or encephalitis. Rarely, adenovirus causes inflammation of the urinary bladder (also known as cystitis), producing blood in the urine. In children, adenoviruses may cause acute upper respiratory infections with fever and runny nose. Adenovirus types 1, 2, 3, 5, and 6 are responsible for most of these infections.
Specific diagnosis of the Adenovirus infection is made by identification of the virus in the patient’s stool. Enzyme linked immunsorbent assay (ELISA) is the test most widely used to screen clinical specimens. Electron microscopy and polyacrylamide gel electrophoresis are used in some laboratories in addition or as an alternative to ELISA.
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