Eagle Biosciences’ Cardiovascular line is a full list of unique assays for the comprehensive determination of important and emerging biomarkers of cardiovascular disease. Our Endothelin (1-21) ELISA and Big Endothelin-1 ELISA are robust and not only offer direct measurement of these analytes but also provide flexibility to run manually or in an automated system. Collectively, these assays provide a comprehensive means to accurately and easily measure the endothelin system and circulating concentrations of endothelin.
EagleBio’s Endothelin Assays offer several key attributes such as excellent sensitivity, use with multiple sample types, and small sample volume requirements which make these assay kits excellent tools for evolving research in cardiovascular and stress-related fields of study.
Why Measure Endothelins?
The principle actions of endothelin surround increasing blood pressure and vascular tone, thus endothelin antagonists may serve to play important roles in offsetting the negative impact endothelin has in invivo. Both Big ET and ET are strong independent predictors of survival in patients
with congestive heart failure, and identify a population with a very high risk of mortality.
The biological role of ET extends beyond endothelins’ primary vascular and growth regulatory properties. Due to the complex nature of the endothelin system, further research may be necessary to further define these biological intricacies for the development of therapeutic agents. Robust, sensitive, and specific immunoassays could be valuable tools to assist researchers in these investigations. Read more
Key Advantages of EagleBio’s Endothelin (1-21) ELISA
- Ultra-sensitivity – quantifies as little as 0.05 pg/ml Endothelin
- Direct measurement: measures both normal and pathological samples -no extraction of samples needed
- Versatility: provides ability to use multiple sample types in various animal species
- Serum Based Standards and Controls: provides biologically reliable data
- Lyophilized Reagents: simplifies procedure with no reagent preparation
- Flexibility: provides ability to run manually and easily with the simple procedure
EageBio offers 1 additional Standard in protein buffered matrix- can be used for spike and recovery experiments, making further standards as required for certain institutions, or for other matrices (i.e. cell culture, species).
Key Advantages of EagleBio’s Big Endothelin-1 ELISA
- Ultra-sensitivity – quantifies as little as 0.02 pmol/ml Endothelin
- Direct measurement: measures both normal and pathological samples -no extraction of samples needed
- Versatility: provides ability to use in serum and plasma
- Serum Based Standards and Controls: provides biologically reliable data
- Lyophilized Reagents: simplifies procedure with no reagent preparation
- Flexibility: provides ability to run manually and easily with the simple procedure
EagleBio’s Big Endothelin-1 ELISA is the only assay available in the market to measure big endothelin-1!
Related Kits:
Endothelin (1-21) ELISA Assay Kit
Big Endothelin-1 ELISA Assay Kit
Related News:
EagleBio Spotlight: Endothelin
Eagle Biosciences Introduces Endothelin 1-21 and Big Endothelin-1 ELISA Kit