The area of a brain lacking Mer and Axl that Salk scientists call the ‘trail of death

Image credit: Salk Institute


Even when the body has reached the peak of development, there are certain regions of the brain where neurons continue to grow. In order to keep these areas neat and clean, the brain recruits immune cells uniquely designed to clear out the dead and dying cells in the brain. Read More

(Source: https://www.labroots.com/trending/immunology/2833/managing-microglia-treating-neurodegenerative-disease)

Further reading

Promising New Target for the Treatment of Chronic Pain




A recent study at the University of Texas at Dallas focused on following the sequence of pain impulses traveling from the brain to the spinal cord in mice.  These researchers were interested in learning more about chronic pain as well as the intricate biological processes and chemicals that are involved. The goal of this research was to better understand the mechanisms that cause and contribute to chronic pain in order to point to more effective treatments. The results of this study revealed that by removing a collection of neurons called A11 that contain dopamine, chronic pain was selectively diminished.

More than 100 million people in the US suffer from chronic pain and it is an extremely costly and debilitating medical condition.  This study and its findings bring promise to new future target medicines. Read More 


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