Multiple genes have been found to be linked to the cause Alzheimer’s disease and result in the disease in different ways. This connection can help better identify targets for prevention therapy by recognizing the different ways the genes lead to neuronal death.
Neurons, astrocytes, oligodendrocytes, and microglial cells are all different cell types found in the brain, specific gene variants had different proportions of these cells in the brain. Scientists at the Washington School of Medicine in St. Louis are working on figuring out how each gene is different and what it does in the brain can help the understanding of how it leads to disease and the best ways to treat it.
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