Human Recombinant Tau-383 (0N4R) Wild-Type Pre-formed Fibrils
The Human Recombinant Tau-383 (0N4R) Wild-Type Pre-formed Fibrils are For Research Use Only
Size: 100 ug
Species: Human
Expression System: E. coli
Buffer: 10mM Hepes pH 7.4, 100mM NaCl
Storage Temperature: -80ºC
Alternative Names: Tau-D, Tau 383
Product manufactured in Canada by StressMarq.
Scientific Background
Several tau isoforms, including 0N4R, are expressed in the human brain, and the existence of multiple human tauopathies with distinct fibril morphologies suggests different molecular conformers incorporating different isoforms may exist. NMR data indicates that both 3R and 4R tau are incorporated into AD-tau seeded fibrils.
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