Human TRAIL R4 ELISA Assay
The Human TRAIL R4 ELISA Assay is For Research Use Only
Size: 1×96 wells
Sensitivity: 64 pg/ml
Dynamic Range: 312.5 pg/ml – 10000 pg/ml
Incubation Time: 3h 40 min
Sample Type: Serum, Cell lysates
Sample Size: 100 µl
Alternative Names: CD264, TRUNND, DcR2
Human Trail R4, also called DcR2, CD264 or TRUNND is a type 1 TNF R family membrane protein which is a receptor for TRAIL. In the Trail receptor family, Trail R4 (DcR2) but also Trail R3 (DcR1) antagonize TRAIL-induced apoptosis whereas Trail R1 (DR4) and Trail R2 (DR5) transducer an apoptosis signal. Trail R4 has a truncated intracellular domain. Overexpression of Trail R4 has been shown to protect cells bearing Trail R1 and/or Trail R2 from Trail-induced apoptosis. Many tumor cell lines don’t express the decoy receptors and are therefore sensitive to TRAIL if they express Trail R1 and/or Trail R2.
Store the Human TRAIL R4/DCR2 ELISA kit reagents between 2 and 8°C. Immediately after use remaining reagents should be returned to cold storage (2-8°C). Expiry of the kit and reagents is stated on box front labels. The expiry of the Human TRAIL R4/DCR2 ELISA Assay kit components can only be guaranteed if the components are stored properly, and if, in case of repeated use of one component, the reagent is not contaminated by the first handling.