What is Anti-Müllerian Hormone (AMH)?
Anti-Müllerian Hormone (AMH) or Müllerian-inhibiting hormone (MIH) is a glycoprotein hormone structurally related to inhibin and activin from the transforming growth factor beta superfamily, whose key roles are in growth differentiation and folliculogenesis. AMH expression is critical to sex differentiation at a specific time during fetal development, and appears to be tightly regulated by nuclear receptor SF1, transcription GATA factors, sex-reversal gene DAX1, and follicle-stimulating hormone
(FSH). AMH is activated by SOX9 in the Sertoli cells of the male fetus thereby
arresting the development of fallopian tubes, uterus, and upper vagina. AMH is
also a product of granulosa cells of the preantral and small antral follicles
in women. As such, AMH is only present in the ovary until menopause. AMH can
serve as a molecular biomarker for relative size of the ovarian reserve and can
also be used as a marker for ovarian dysfunction, such as in women with
polycystic ovary syndrome (PCOS).
What Makes Eagle Biosciences AMH Assay Different?
Compared to other products on the market, our Anti-Müllerian Hormone ELISA Assay Kit provides a much simpler procedure with less washes and incubation time. Eagle Biosciences Human Anti-Müllerian Hormone ELISA Assay kit is intended for use in the quantitative determination of human Anti-Mullerian Hormone (AMH) levels in serum, EDTA plasma and lithium heparin plasma samples.
|Dynamic Range||0.11-20 ng/mL|
|Incubation Time||4.5 hours|
|Sample Size||50 µL|