Fibroblast growth factor 21 has no direct role in regulating fertility in female mice

EagleBio’s Intact FGF-21 ELISA Kit was recently cited in Boston Study:

“Recently, another nutritionally regulated hormone, FGF21, has
been proposed as a regulator of fertility in rodents based on the finding that
female mice overexpressing FGF21 to supraphysiologic levels (FGF21-Tg) have
delayed onset of puberty and remain infertile through adulthood
[13]. In
this proposed model, FGF21 synthesized and secreted into the circulation by the
liver acts on the SCN to suppress the production of vasopressin (
AVP) which further suppresses kisspeptin-1 (Kiss-1), an important regulator of fertility.” Read More