Biomarker of urinary 5-HIAA as a valuable predictor of acute appendicitis

Science Direct

Acute appendicitis is one of the most common causes of severe acute abdominal pain globally. Increased levels of 5-Hydroxyindole acetic acid (5-HIAA), a metabolite of serotonin, in urine has been associated with acute appendicitis due to the densely packed serotonin-containing cells in the appendix. A study performed recently aimed to evaluate and determine the significance of 5-HIAA as a diagnostic marker.

Read the full article here.


Eagle Biosciences offers a sensitive and reliable assay for the detection of 5-HIAA in urine samples:

5-HIAA ELISA Assay Kit

Serotonin ELISA Assay Kit

Serotonin Ultrasensitive ELISA Assay Kit

If you are looking for any other specific 5-HIAA related product or if you have questions about our offerings, contact us here.

EagleBio’s Serotonin ELISA was used in a Michigan State Univeristy study (see citation below).  This is a kit from our Neurobiology Assay Kit line. The Neurobiology Assay Kit line offered Eagle Biosciences provides a comprehensive array of sensitive tools to measure catecholamines and numerous neuroscience-related analytes on various types of samples. 

Plasma serotonin levels were determined in this study using Eagle Biosciences’ Serotoinin ELISA:

Joshi, N. Inhibition of PAR-4 and P2Y12 receptor-mediated platelet activation produces distinct hepatic pathologies in experimental xenobiotic-induced cholestatic liver disease. Toxicology. 2016; 365:9-16.

New Study Referencing EagleBio’s Serotonin ELISA Assay Kit




EagleBio continuously has researchers publishing new literature referencing our kits for a variety of our product lines. A recent study was conducted by Johns Hopkins University School of Medicine utilizing a kit from our Neurobiology Assay Kit line. The Neurobiology Assay Kit line offered Eagle Biosciences provides a comprehensive array of sensitive tools to measure catecholamines and numerous neuroscience-related analytes on various types of samples. Check the product pages for full details on the kit or view the links below to find a new publication referencing our  Serotonin ELISA Assay Kit.


New Publication:

Quinolinic acid/tryptophan ratios predict neurological disease in SIV-infected macaques and remain elevated in the brain under cART


Related News:

EagleBio Assay Kits in Several New Publications

January 21, 2015- Eagle Biosciences Shares Some New Publications Across Multiple EagleBio Assay Kit Product Lines

Related Kits:

Neurobiology Assay Kits

Catecholamine Assay Kits

​EagleBio Assay Kits in Several New Publications


EagleBio offers numerous unique and robust kits in a variety of emerging areas of research and disciplines. There are several publications to date for the assays but there some new publications to highlight for our Endocrine Assay Kits, Oxidative Stress Assay KitsCancer Biomarker Kits product lines. Check out the product pages for full information on the kits, or view the links below for the new publication details.


Mouse /
Rat GLP-1 Active (7-36) ELISA Kit

Publication:

The Pancreapedia: Exocrine Pancreas Knowledge Base


Rat Tissue Type Plasminogen Activator (TPA) Total ELISA Assay Kit

Publication:

Locally Increased Concentrations of Inflammatory Cytokines in an Experimental Intraabdominal Adhesion Model


Serotonin ELISA Assay Kit

Publication:

Combination Fluconazole/Paroxetine Treatment is Neuroprotective Despite Ongoing Neuroinflammation and Viral Replication in an SIV model of HIV Neurological Disease