Category: New Product Series

Eagle Biosciences is excited to announce a new line of cytokine assays!

About Cytokines

Cytokines are a cornerstone of any study that deals with inflammation. Cytokine profiles as a whole and the relative abundance of one cytokine, and the endogenous inhibitors, define an inflammatory process that is in motion. Specific cytokines of interest include interleukins, interferons, chemokins, and members of the tumor necrosis factor and TGF beta super families.

Cytokine sandwich ELISA are sensitive enzyme immunoassays that can specifically detect and quantitate the concentration of soluble cytokine and chemokine proteins. They allow researchers to study the complicated physiological and pathological roles of cytokines in systemic inflammatory reactions, and accurately measure the levels of specific cytokines under physiological and pathological conditions which can provide valuable insight into the changes associated with different disease states.

Our Available Cytokine Assays

Human IL-4 ELISA Assay Kit
Human IL-6 High Sensitivity ELISA Assay Kit
Human IL-10 ELISA Assay Kit
Mouse IL-4 ELISA Assay Kit
Mouse IL-8 ELISA Assay Kit
Mouse IL-12 ELISA Assay Kit
Rat IFN-gamma ELISA Assay Kit
Rat IL-2 ELISA Assay Kit
Rat IL-4 ELISA Assay Kit
Rat IL-8 ELISA Assay Kit
Rat IL-10 ELISA Assay Kit
Rat IL-12/P40 ELISA Assay Kit
VEGF ELISA Assay Kit
Angiopoietin-2 ELISA Assay Kit

If you have any questions about our offerings contact us here.

Eagle Biosciences is excited to announce the Human IL-6 High Sensitive ELISA Assay Kit from Biomedica! This powerful kit offers a wide dynamic range with extraordinary sensitivity. It provides superior performance and reliability for all your researching needs.

About Interleukin-6 (IL-6)

IL-6 is a pleiotropic cytokine that plays a crucial role in regulating the acute phase response, inflammation, hematopoiesis, glucose metabolism, bone metabolism, and cancer progression. IL-6 is an early marker of acute inflammation. In patients with COVID-19, IL-6 levels are significantly elevated and associated with adverse clinical outcomes. Therefore, serum IL-6 is an important biomarker for severity of COVID-19 and has great potential for guiding treatment of the disease.

IL-6 can reliably be measured by ELISA (cat.no. BI-IL6) in human serum, plasma and urine samples with Biomedica’s fully validated assay kit. The kit is highly sensitive and offers a wide dynamic range. The kit incorporates ready to use standards and controls.

Features & Benefits of the Human IL-6 High Sensitive ELISA Assay Kit

√ EASY ready to use calibrators & controls included
√ High SENSITIVITY measurable values in serum and plasma
√ Full validation package – the assay is optimized for clinical samples
√ HIGH QUALITY GUARANTEED

Related publications:

Interleukin-6 in Covid-19: A systematic review and meta-analysis. Coomes EA, Haghbayan H. Rev Med Virol. 2020 Nov;30(6):1-9. Full text.

Assessing the importance of interleukin-6 in COVID-19. Chen LYC, Hoiland RL, Stukas S, Wellington CL, Sekhon MS. Lancet Respir Med. 2021 Feb;9(2):e13. Full text.

If you have any questions about the Human Il-6 High Sensitive ELISA Assay Kit or any of our other offerings, contact us here.

Eagle Biosciences announces new Polystreptavidin R (Polystrept R) Extraordinary high Biotin binding capacity! This reagent is for surface coating of plastics, membranes, beads and etc. with maximum biotin binding capacity. It improves the signal-noise-relation and saves material costs.

About Streptavidin

Streptavidin is a tetrameric protein (4 x 13 kDa), which binds very tightly to the small molecule Biotin. The binding constant for this interaction is extremely high (Ka ~ 1013 M-1) and turns the Streptavidin/Biotin system into a basis of many biochemical applications. Streptavidin-coated surfaces are characterized by very low nonspecific bindings. Streptavidin coating of solid phases offers a universal immobilization principle for the detection and analysis of proteins, peptides, PCR-fragments etc.

About Polystreptavidin R

Polystreptavidin R is characterized by a immensely high biotin binding capacity in combination with robustness against thermal and chemical influences. Polystreptavidin R is easy to use and suitable for coatings on membranes, beads, microplates, biochips and other plastic materials.

Polystreptavidin R at the strip test (lateral flow assay)

Polystreptavidin R shows outstanding properties when coated on nitrocellulose membranes. The very high biotin binding capacity and the very low washout effects provide a significant signal enhancement at the test line. Highly efficient immobilization of biotinylated molecules and low non-specific binding provide a high signal-to-noise ratio. Polystreptavidin R is a liquid concentrate and can be easily diluted with a neutral buffer for coating or spotting and dried at room temperature without any further production steps. If required, stabilizers can also be added. At temperatures of 2°C to 50°C Polystreptavidin R is stable for at least 24 months and supports a long shelf life.

Why use streptavidin-coated microplates and Polystrept R with lateral flow test strips?

• Convenient method for a uniform and stable immobilization of biotinylated molecules
• Immobilization of Biomolecules on solid phases in a directed manner, while avoiding or minimizing denaturation
• Ready-to-use, no washing or blocking steps required
• High signal-to-noise ratio
• Low nonspecific binding
• Long shelf life
• Lower reagent consumption and especially enormous cost savings with lateral flow test stripes

Related Products

Ultra-Sensitive Streptavidin Coated Clear 96 Well Microplate
Biotin Microtiter Plate Assay

If you have any questions about Polystreptavidin R or our other offerings, contact us here.