C5, a key 190kDa protein in the complement system, is vital for both innate and adaptive immune responses. It spearheads protective actions against pathogens, paving the way for adaptive immunity. Present in blood, tissues, and body fluids, C5 forms part of the complex complement system. Its activation, through classical, lectin, and alternative pathways, leads to the formation of the Membrane Attack Complex (MAC). This complex is critical for neutralizing harmful microorganisms and damaged cells. Yet, uncontrolled C5 activation is linked to diseases like asthma, lupus, and multiple sclerosis. Genetic mutations causing C5 deficiency result in recurrent bacterial infections, highlighting its crucial role in immunity. C5’s importance extends beyond immune defense, positioning it as a target for treating various immune-related disorders. This underscores the significance of C5 in immune system function and disease management.
This product is manufactured in Netherlands by Hycult Biotech.
| Size | 1 x 96 Well |
| Sensitivity | 3.1 ng/mL |
| Dynamic Range | 3.1 – 200 ng/mL |
| Incubation Time | 3 hours 30 minutes |
| Sample Type | Serum, Plasma |
| Storage | 2-8°C |
| Alternative Names | Complement C5 Protein |