Rabbit Anti-Human HSP70 Acetyl Lys77 Polyclonal Antibody
HSP70 proteins are a highly conserved family of 70-kDa molecular chaperones that play a central role in protein folding, stabilization, and transport across nearly all cellular compartments—including the cytosol, nucleus, mitochondria, endoplasmic reticulum, and chloroplasts. These proteins are encoded by a multigene family and are upregulated in response to cellular stress, making them key regulators of proteostasis.
The HSP70 Acetylated Lysine 77 Antibody is a powerful tool for detecting HSP70 proteins specifically modified at lysine 77, a post-translational modification (PTM) that may influence chaperone activity, protein-protein interactions, and cellular localization. Acetylation at this site occurs within the highly conserved N-terminal ATP-binding domain, which is essential for HSP70’s conformational cycling and substrate release.
This antibody may help researchers to monitor acetylation-specific regulation of HSP70 under stress conditions; investigate the role of lysine 77 acetylation in neurodegenerative diseases, cancer, and aging; or differentiate between modified and unmodified HSP70.
This Rabbit Anti-Human HSP70 Acetyl Lys77 Polyclonal Antibody is manufactured in Canada by StressMarq.
![Human [Leu60] IGF-I](https://eaglebio.com/wp-content/uploads/2025/08/GroPep-logo-header-1-418x418.png){kind=logo}
