Mouse Anti-Human DENND4C Monoclonal IgG1 Antibody
DENND4C is a guanine nucleotide exchange factor (GEF) for Rab10, a small GTPase involved in vesicle trafficking and membrane recycling. DENND4C regulates GLUT4 translocation and interacts with the retromer complex, linking it to endosomal sorting and cellular metabolism.
Mutations in DENND4C have been associated with neurodevelopmental syndromes such as Alkuraya-Kucinskas and Koolen-De Vries, suggesting a broader role in brain development and function. Its involvement in membrane trafficking pathways positions DENND4C as a candidate for investigation in neurodegenerative diseases characterized by endolysosomal dysfunction.
This Mouse Anti-Human DENND4C Monoclonal IgG1 Antibody is manufactured in Canada by StressMarq.
| Size | 100 µg |
| Group | |
| Alpha Chain | |
| Beta Chain | |
| Peptide | |
| Peptide Source | |
| Format | |
| Buffer | |
| Concentration | 1mg/mL |
| Storage | -20°C |
| Alternative Names | DENN domain-containing protein 4C |
